Search for dissertations about: "Margareta Halin Lejonklou"

Found 2 swedish dissertations containing the words Margareta Halin Lejonklou.

  1. 1. The MEN 1 Pancreas : Tumor Development and Haploinsufficiency

    Author : Margareta Halin Lejonklou; Britt Skogseid; Peter Stålberg; Andreea Barbu; Gerard Doherty; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEN 1; PNET; tumor development; haploinsufficiency; survivin; Endokrinologi och Diabetologi; Endocrinology and Diabetology;

    Abstract : Multiple Endocrine Neoplasia Type I Syndrome (MEN 1) is a monogenic autosomal dominantly inherited cancer syndrome caused by a heterozygous loss of the MEN1 gene, predisposing for endocrine cell proliferation and tumor formation. MEN 1 carriers classically develop tumors in endocrine organs; the parathyroids, the endocrine pancreas, and the pituitary. READ MORE

  2. 2. Exposure to Bisphenol A (BPA) and Metabolic Disruption

    Author : Linda Dunder; Monica Lind; Margareta Halin Lejonklou; Lars Lind; Anna-Maria Andersson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Bisphenol A BPA ; Endocrine disrupting chemicals EDCs ; Developmental exposure; Metabolic disruption; Adipose tissue; Fatty acids; Insulin secretion; Experimental rat study; Epidemiology; Medicinsk vetenskap; Medical Science;

    Abstract : Metbolic disorders such as obesity, type 2 diabetes, liver lipid disorders and metabolic syndrome are increasing rapidly and have largely been attributed to genetic background and changes in diet, exercise and aging. However, there is now considerable evidence showing that other environmental factors, including environmental chemicals, may contribute to the rapid increase in the incidence of these metabolic diseases. READ MORE