Search for dissertations about: "Maria Faresjö"
Showing result 1 - 5 of 11 swedish dissertations containing the words Maria Faresjö.
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1. Immunological profile and aspects of immunotherapy in type 1 diabetes
Abstract : Type 1 diabetes (T1D) is a chronic, autoimmune disease caused by a T cell mediated attack on the insulin producing pancreatic ß-cells. Even though reasonable quality of life can be acquired with modern insulin therapy, prevention of acute and late serious complications is facilitated by preservation of residual insulin secretion. READ MORE
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2. Exploring vitamin D and steroid hormone receptors – from healthy elderly to prostate cancer cells
Abstract : The genetic background together with environmental factors and lifestyle are key contributors to the health of an individual. Genetic background is inherited and irreversible unless mutations occur. However, lifestyle habits (i.e. READ MORE
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3. Exploration of Conditions Affecting Cytokine Production in Experimental Type 1 Diabetes Mellitus
Abstract : Cytokines are soluble signalling mediators within the immune system, and have been shown to be of importance in the development of type 1 diabetes (T1D). This thesis studied the production of cytokines in experimental models of T1D and during transplantation of insulin-producing islets of Langerhans. READ MORE
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4. Repurposing digitoxin in the treatment of pancreatic ductal adenocarcinoma : genotypic and phenotypic features as biomarkers for digitoxin sensitivity in vitro
Abstract : The incidence of pancreatic ductal adenocarcinoma (PDAC) is increasing worldwide. The dismal prognosis and lack of effective treatments urges for increased research efforts in developing new treatment regimens. Since the development of new cancer treatments are expensive and time consuming, repurposing drugs is preferable when possible. READ MORE
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5. The importance of psychological and physical stressors on diabetes-related immunity in a young population – an interdisciplinary approach
Abstract : Background: The prevalence of immunological disorders such as type 1 diabetes (T1D) is increasingly common amongst children, adolescents and young adults. There is also an increase in psychosomatic symptoms (depression, insomnia, anxiety, headaches and fatigue etc. READ MORE