Search for dissertations about: "Maria Sunnerhagen"
Showing result 6 - 10 of 13 swedish dissertations containing the words Maria Sunnerhagen.
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6. Development and Application of Computational Models for Peptide-Protein Complexes
Abstract : Protein-protein interactions between a protein and a smaller protein fragment or a disordered segment of a protein are called peptide-protein interactions. Such interactions are commonplace in nature and vital for normal cell function in humans. READ MORE
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7. Regulation of the multi-functional protein YscU in assembly of the Yersinia type III secretion injectisome
Abstract : Yersinia pseudotuberculosis is a Gram-negative zoonotic pathogenic bacterium causing gastroenteritis in human and animals. It shares a conserved virulence plasmid encoding for a needle-like secretion machinery, or type III secretion system, which can be found in other pathogenic Gram-negative bacteria. READ MORE
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8. Small angle scattering as a tool to study protein structure and interactions
Abstract : This thesis uses small angle X-ray and neutron scattering (SAXS/SANS) to gain structural and functional insight into the molecular regulation of critical life processes in prokaryotic and eukaryotic species. The presented studies highlight the strength of combining low-resolution structure determination with biophysical and in silico modelling methods to extensively characterize proteins and their interactions. READ MORE
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9. On protein structure, function and modularity from an evolutionary perspective
Abstract : We are compounded entities, given life by a complex molecular machinery. When studying these molecules we have to make sense of a diverse set of dynamical nanostructures with wast and intricate patterns of interactions. READ MORE
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10. Structural, Dynamic and Functional Studies of USP14 : A Proteasome-Associated Deubiquitinating Enzyme Regulating Protein Degradation
Abstract : Ubiquitin-Specific Protease 14 (USP14) is a proteasome-associated deubiquitinating enzyme (DUB) involved in regulation of protein degradation and recycling of ubiquitin. USP14 consists of a Ubl domain connected to a USP domain via a flexible linker. READ MORE