Search for dissertations about: "Maria Wahlbom"

Found 1 swedish dissertation containing the words Maria Wahlbom.

2. 1. Domain swapping as a molecular mechanism in amyloidosis

   Author : Maria Wahlbom; Avdelningen för klinisk kemi och farmakologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Clinical chemistry; Klinisk kemi; Medicin människa och djur ; Medicine human and vertebrates ; oligomer; dimer; domain swapping; fibril; cystatin C; amyloidosis;

   Abstract : Amyloidosis is a group of diseases characterized by a change in protein conformation resulting in aggregation and tissue deposition of amyloid fibrils. One variant of cystatin C, L68Q cystatin C, is highly amyloidogenic and persons carrying the corresponding gene suffer from massive cerebral amyloidosis leading to brain hemorrhage and death. READ MORE