Search for dissertations about: "Martin Boström"

Found 2 swedish dissertations containing the words Martin Boström.

  1. 1. Genomic mutational heterogeneity in cancer. lmproved models and tools for driver gene detection

    Author : Martin Boström; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cancer; genomics; ultraviolet light; mutational heterogeneity;

    Abstract : Cancer is a disease that is strongly related to evolution, as mutations that confer a benefit to individual cells face positive selection and eventually lead to tumorigenesis. As such, the search for genes that drive cancer development entails distinguishing positive selection from other sources of increased mutation rates, which requires detailed knowledge of how normal mutation rates vary across the genome. READ MORE

  2. 2. Rectal cancer : the influence of surgical technique on morbidity, mortality and survival

    Author : Petrus Boström; Martin Rutegård; Markku Haapamäki; Peter Matthiessen; Jörgen Rutegård; Martyn Evans; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; rectal cancer; anterior resection; high ligation; level of tie; anastomotic leakage; postoperative pain;

    Abstract : Surgery is still the most common treatment for rectal cancer, being the most effective and cost-efficient modality. However, it is not without risk, nor without controversies. READ MORE