Search for dissertations about: "Martin Moche"

Found 2 swedish dissertations containing the words Martin Moche.

  1. 1. Crystallographic studies of enzymes involved in biosynthesis of fatty acids : Beta-ketoacyl acyl carrier protein synthase II and delta9-stearoyl-ACP desaturase

    Author : Martin Moche; Karolinska Institutet; Karolinska Institutet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP;

    Abstract : In the biosynthesis of fatty acids, the beta-Ketoacyl Acyl Carrier Protein Synthases (Kas) catalyse chain elongation by the addition of two-carbon units derived from malonyl-ACP, to an acyl group bound to CoA or the small protein ACP. These enzymes are potential targets for antibiotics against bacterial or parasitical infections and their mammalian counterparts could hopefully be used as drug targets against certain cancers and obesity. READ MORE

  2. 2. Structural insights into protein-protein interactions governing regulation in transcription initiation and ubiquitination

    Author : Madhanagopal Anandapadamanaban; Maria Sunnerhagen; Martin Moche; Marie Wahren-Herlenius; Cynthia Wolberger; Linköpings universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : Virtually every aspect of the cellular processes in eukaryotes requires that the interactions between protein molecules are well coordinated in different regulatory pathways. Any protein dysfunction involved in these regulatory pathways might lead to various pathological conditions. READ MORE