Search for dissertations about: "Martin Simonsson"

Found 1 swedish dissertation containing the words Martin Simonsson.

  1. 1. Quantification of Radiation Induced DNA Damage Response in Normal Skin Exposed in Clinical Settings

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Martin Simonsson; Uppsala universitet.; [2011]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; DNA damage response; low-dose hypersensitivity; dose response; normal tissue; epidermis; dermis; keratinocyte; fractionated radiotherapy; DNA double strand break; DSB; foci; gamma-H2AX; 53BP1; p21; checkpoint; apoptosis; mitosis; micro-RNA; miR-34a; MEDICINE Surgery Oncology; MEDICIN Kirurgi Onkologi; Oncology; Onkologi;

    Abstract : The structure, function and accessibility of epidermal skin provide aunique opportunity to study the DNA damage response (DDR) of a normaltissue. The in vivo response can be examined in detail, at a molecularlevel, and further associated to the structural changes, observed at atissue level. READ MORE