Search for dissertations about: "Mast cell"

Showing result 1 - 5 of 167 swedish dissertations containing the words Mast cell.

  2. 1. Molecular Studies of Mast Cell Migration and Apoptosis : Two Ways of Regulating Mast Cell Numbers at Sites of Inflammation

    Author : Jessica Alfredsson; Gunnar Nilsson; Hans-Uwe Simon; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pathology; mast cell; SCF; IL-3; FcεRI; migration; apoptosis; Bim; Bcl-2; Bcl-XL; Akt; FOXO; MAPK; Patologi; Pathology; Patologi;

    Abstract : Upon activation mast cells release numerous proinflammatory mediators. With this feature, mast cells play an important role in host defense against pathogens, and are involved in tissue remodeling and wound healing. However, in cases of excessive inflammation the effects of mast cells are detrimental. READ MORE

  4. 2. Regulation of Mast Cell Survival

    Author : Christine Möller; Gunnar Nilsson; Alf Grandien; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pathology; mast cell; A1; Bfl-1; Bim; Bcl-2 family members; basophil; SCF; forkhead; survival; Patologi; Pathology; Patologi;

    Abstract : Mast cells are long-lived effector cells of importance for both acute and chronic inflammations. Mast cells can be activated in many different ways, leading to the release of inflammatory mediators. In contrast to most other inflammatory cells, activated mast cells have the capacity to recover, regranulate and thereby be activated again. READ MORE

  5. 3. Mast Cell Migration in Inflammatory Diseases

    Author : Niclas Olsson; Gunnar Nilsson; Jaroslaw Dastych; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pathology; Mast cells; chemotaxis; inflammation; Patologi; Pathology; Patologi;

    Abstract : Mast cells (MCs) are forceful multifunctional effector cells of the immune system. MCs are normally distributed throughout connective and mucosal tissues, but in several pathological conditions accumulation of MCs occur. READ MORE

  6. 4. Mast cells in Hodgkin lymphoma : or 'What's a nice cell like you doing in a tumour like this?'

    Author : Marie Fischer; Gunnar Nilsson; Gunilla Enblad; Tor Olofsson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pathology; Hodgkin lymphoma; mast cells; CD30; CD30L; IL-9; CCL5; atopic dermatitis; psoriasis; IL-8; Patologi; Pathology; Patologi;

    Abstract : Mast cell (MC) accumulation around tumours is an old observation gaining new relevance due to the multifaceted nature of MCs and their many roles in immunity, beyond allergy. Knowledge about tumour specific recruitment of, and interactions with, MCs is needed to unravel the function of their presence. READ MORE

  7. 5. The Role of Chemokines in Mast Cell Migration

    Author : Mikael Juremalm; Timothy J. Williams; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pathology; Mast cells; chemotaxis; calcium flux; chemokines and chemokine receptors; Patologi; Pathology; Patologi; Pathology; patologi;

    Abstract : Mast cells are very potent multifunctional effector cells of the immune system normally distributed throughout connective tissues. An accumulation of mast cells has been described in several pathological conditions such as allergic- and autoimmune inflammations and in certain tumours. READ MORE