Search for dissertations about: "Mast cells"

Showing result 16 - 20 of 177 swedish dissertations containing the words Mast cells.

  2. 16. Neuroimmune Interactions of Enteric Neurons and Mast Cells: Friends or Foes?

    Author : Elin Sand; Neurogastroenterologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; enteric neurons; ischemia; VIP; mast cells; CRF;

    Abstract : Psychological distress or physical strain lead to reduced blood flow in the intestine since other organs are prioritised. One aim of this thesis was to investigate how ischemia followed by reperfusion affects the large intestine and the enteric nervous system (ENS). READ MORE

  4. 17. Regulation of human mast cell development

    Author : Malin Hjertson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; Mast cells; hematopoiesis; chemotaxis; SCF; FL; GM-CSF; IL-3; RA; SDF-1; Genetik; Clinical genetics; Klinisk genetik; Pathology; patologi;

    Abstract : Mast cells are multifunctional effector cells of the immune system and are best known for theirparticipation in allergic reactions. The aim of this thesis was to investigate how the stem cell factor(SCF)-dependent development of mast cells from cord blood can be regulated by different factors, and tostudy how immature mast cells circulating in the blood can be recruited into the tissue. READ MORE

  5. 18. The Role of Fc gamma Receptors and Mast Cell Chymase in Autoimmune Arthritis

    Author : Sofia Magnusson; Sandra Kleinau; Jeanette Leusen; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; fc gamma receptors; rheumatoid arthritis; antibodies; mast cells; mast cell; Immunology; Immunologi; Immunologi; Immunology;

    Abstract : In autoimmune diseases such as rheumatoid arthritis (RA), self-reactive antibodies are present at high levels, which contributes to disease pathogenesis. The antibodies mediate their effect predominantly by binding to Fc gamma receptors (FcγR) on various leukocytes, such as monocytes, macrophages and mast cells, where FcγR ligation leads to cell activation. READ MORE

  6. 19. Signal Transduction in Mast Cell Migration

    Author : Magnus Sundström; Bengt Hallberg; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; HMC-1; Kit; MAP kinase; mast cells; mastocytosis; p38; SCF; TGF-β; Genetik; Clinical genetics; Klinisk genetik; Pathology; patologi;

    Abstract : Mast cells are essential effector cells in the immune system as they release several inflammatory mediators. An accumulation of mast cells has been described in inflammatory conditions such as asthma and allergic rhinitis. READ MORE

  7. 20. New Aspects of Mast Cell Progenitors in Health and Disease

    Author : Maya Salomonsson; Jenny Hallgren Martinsson; Silvia Bulfone-Paus; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Mast cells; Mast cell progenitor; Lung function; Bone marrow; Blood; Activation; Chemotactic receptors;

    Abstract : Mast cells are tissue-resident immune cells that are well known for their involvement in asthma and allergy. They originate in the fetal yolk sac, or in the bone marrow. From the bone marrow, they are released as immature progenitors that are transported via the blood circulation to the peripheral tissue, where they mature. READ MORE