Search for dissertations about: "Matrix-Assisted Laser Desorption Ionization Mass Spectrometry"
Showing result 1 - 5 of 49 swedish dissertations containing the words Matrix-Assisted Laser Desorption Ionization Mass Spectrometry.
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1. Electrophoretic focusing in microchannels combined with mass spectrometry : Applications on amyloid beta peptides
Abstract : Analysis of low-abundance components in small samples remains a challenge within bioanalytical chemistry, and new techniques for sample pretreatments followed by sensitive and informative detection are required. In this thesis, procedures for preconcentration and separation of proteins and peptides in open microchannels fabricated on silicon microchips are presented. READ MORE
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2. Label free analysis and spatial distribution of molecular lipids in brain tissue and cells using mass spectrometry imaging
Abstract : Lipids are important inherent components in brain and cell membranes, which play significant biological roles in cell function. Identification and localization of specific biomolecules such as peptides and lipids within cellular membranes is currently a major challenge in metabolomics and biological studies. READ MORE
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3. Tools for applied soft ionization mass spectrometry
Abstract : Mass spectrometry (MS) is an important analytical tool. Its most importantadvantages are sensitivity, resolution, and accurate and precise m/zmeasurements. To get the best results from an instrument, the user musthave knowledge of its limitation and requirements. READ MORE
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4. Sample preconcentration in open microchannels : Combinations with MALDI and nano-ESI mass spectrometry and computer simulations
Abstract : In this thesis a novel concept for preconcentration of biomolecules in open microchannels is presented. The preconcentration is based on electromigration of charged analytes, and detection is performed with matrix-assisted laser desorption/ionization (MALDI) or nano-electrospray ionization (nESI) mass spectrometry (MS). READ MORE
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5. Development of Methods for Protein and Peptide Analysis Applied in Neuroscience Utilizing Mass Spectrometry
Abstract : This thesis describes the utilization of the matrix-assisted laser desorption ionization mass spectrometry (MALDI MS) and electrospray ionization (ESI) MS techniques for analysis of complex brain tissue samples. Direct molecular profiling of biological samples using MALDI MS is a powerful tool for identifying phenotypic markers. READ MORE