Search for dissertations about: "Matrixbiologi"

Found 5 swedish dissertations containing the word Matrixbiologi.

  2. 1. Aspects on dermatan sulfate metabolism

    Author : Erik Eklund; Matrixbiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Klinisk biologi; Clinical biology; iduronic acid; galactosaminoglycan; Dermatan sulfate; biosynthesis;

    Abstract : The functions of proteoglycans often depend on the fine structure of the covalently attached glycosaminoglycan (GAG) side-chains. The process leading to the mature GAG is complex and involves a multitude of different enzymatic steps. READ MORE

  4. 2. FROM GENE TO STRUCTURE: Formation of Iduronic Acid in Dermatan Sulfate by Two DS-epimerases

    Author : Benny Pacheco; Matrixbiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : During embryonic development and adult life a wide range of cell behaviors such as differentiation, proliferation and migration are in effect to maintain tissue integrity and function. An integral part of these dynamic processes is the interplay between the cells and their environment, i.e. the extracellular space. READ MORE

  5. 3. Biological Functions of Iduronic Acid in Chondroitin/Dermatan Sulfate in Tumor and Brain Development

    Author : Martin Thelin; Matrixbiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; iduronic acid; chondroitin sulfate; esophagus squamous cell carcinoma; cancer; MET receptor; dermatan sulfate; hepatocyte growth factor; DS-epimerase 2; DS-epimerase 1;

    Abstract : Cell behavior such as migration and proliferation, especially during cancer development, are balanced by the surrounding environment. Complex polysaccharides called glycosaminoglycans (GAGs) are part of this environment and they are known to modulate tumor development. READ MORE

  6. 4. Uterine Remodeling During Pregnancy - Studies on the Effect of Heparin/Heparan Sulfate

    Author : Anna Åkerud; Matrixbiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : During pregnancy, the uterine tissues must go through a major transformation to be able to first hold the growing fetus and then, at term, expel it through the opened birth canal (cervix). It is a requirement for successful labor that there is adequate cervical softening combined with effective myometrial contractions. READ MORE

  7. 5. Fibromodulin and Dystrophin in Atherosclerosis: Novel roles for extracellular matrix in plaque development

    Author : Annelie Shami; Kärlväggsbiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Atherosclerosis; fibromodulin; dystrophin; carotid artery; lipid accumulation; restenosis; plaque;

    Abstract : Cardiovascular disease represents nearly half the cases of noncommunicable diseases worldwide and is the leading global cause of death. The main underlying cause is atherosclerosis, and in atherosclerotic plaque progression the structure, composition and integrity of a dynamic extracellular matrix (ECM) is one very important factor. READ MORE