Search for dissertations about: "Mats G. Eriksson"

Showing result 1 - 5 of 13 swedish dissertations containing the words Mats G. Eriksson.

  1. 1. Direct Thrombin Inhibitors in Treatment and Prevention of Venous Thromboembolism: Dose – Concentration – Response Relationships

    Author : Marie Cullberg; Mats O. Karlsson; Ulf G. Eriksson; Nick H.G. Holford; Uppsala universitet; []
    Keywords : Pharmaceutical biosciences; Ximelagatran; pharmacokinetic; pharmacodynamic; activated partial thromboplastin time; utility function; dosing strategy; venous thromboembolism; NONMEM; Farmaceutisk biovetenskap;

    Abstract : For prevention and treatment of thrombotic diseases with an anticoagulant drug it is important that an adequate dose is given to avoid occurrence or recurrence of thrombosis, without increasing the risk of bleeding and other adverse events to unacceptable levels. The aim of this thesis was to develop mathematical models that describe the dose-concentration (pharmacokinetic) and concentration-response (pharmacodynamic) relationships of direct thrombin inhibitors, in order to estimate optimal dosages for treatment and long-term secondary prevention of venous thromboembolism (VTE). READ MORE

  2. 2. Landscape and soil erosion history in central Tanzania : a study based on lacustrine, colluvial and alluvial deposits

    Author : Mats G. Eriksson; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Soil erosion; Soil degradation; Tanzania;

    Abstract : .... READ MORE

  3. 3. Polybrominated diphenyl ethers and Tetrabromobisphenol A : Chemical synthesis, X-ray crystallography and Photochemical degradation

    Author : Johan Eriksson; Åke Bergman; Lars Eriksson; Mats Tysklind; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Environmental chemistry; Miljökemi;

    Abstract : In the 1960s’ several manmade chemicals were detected in the environment, far from their sources. The most well known, and most likely those with the largest impact on the society, were DDT and its related compounds, and PCBs. These anthropogenic compounds were characterised as persistent organic pollutants (POPs). READ MORE

  4. 4. Trust in Biobank Research : Meaning and Moral Significance

    Author : Linus Johnsson; Mats G. Hansson; Gert Helgesson; Stefan Eriksson; Berge Solberg; Uppsala universitet; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Biobank; biobank research; bioethics; biobank ethics; research ethics; trust; trustworthiness; moral responsibility; informed consent; ethics review; ethics guidelines; Bioetik; Bioethics;

    Abstract : What role should trust have in biobank research? Is it a scarce resource to be cultivated, or does its moral significance lie elsewhere? How does it relate to the researcher’s individual responsibility?In this thesis I draw four general conclusions. First, trust is still very much present in at least some biobanking settings, notably in Sweden, but possibly also internationally. READ MORE

  5. 5. Biobank Research : Individual Rights and Public Benefit

    Author : Joanna Stjernschantz Forsberg; Stefan Eriksson; Mats G. Hansson; Angus Dawson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biobank; Ethics; Consent; Returning results; Individual rights; Public good; Medicinsk vetenskap; Medical Science;

    Abstract : The aim of this thesis is to investigate the relationship between individuals and society in the context of healthcare and medical research, more specifically concerning the rights and duties of individuals in regard to biobank-based research. My starting point is that we all have a strong vested interest in improved healthcare, and therefore the possibilities to conduct important research should be optimized. READ MORE