Search for dissertations about: "Mats O. Magnusson"

Found 1 swedish dissertation containing the words Mats O. Magnusson.

2. 1. Pharmacodynamics of Enzyme Induction and its Consequences for Substrate Elimination

   Author : Mats O. Magnusson; Rikard Sandström; Mats Karlsson; Ulf Bredberg; Uppsala universitet; []
   Keywords : Pharmacokinetics Pharmacotherapy; Pharmacokinetics; Pharmacodynamics; Enzyme induction; Time course; Turnover model; Mechanism-based; Modelling; NONMEM; Farmakokinetik Farmakoterapi;

   Abstract : Enzyme induction is a process whereby a molecule enhances the expression of enzymes. If the affected enzymes are involved in the elimination of a drug, this may result in a drug interaction. Induction is therefore of major concern during drug development and in clinical practice. READ MORE