Search for dissertations about: "Matthew Webster"
Found 4 swedish dissertations containing the words Matthew Webster.
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1. Meiotic Recombination in Human and Dog : Targets, Consequences and Implications for Genome Evolution
Abstract : Understanding the mechanism of recombination has important implications for genome evolution and genomic variability. The work presented in this thesis studies the properties of recombination by investigating the effects it has on genome evolution in humans and dogs. READ MORE
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2. Population genomic analyses of regulatory variation and selection in Brassicaceae species
Abstract : The impact of selection on regulatory variation and the contribution of regulatory changes to phenotypic variation has long been debated in evolutionary genetics. Because cis-regulatory elements such as promoters and enhancers can be difficult to identify, it has been more challenging to quantify the impact of selection on variation in cis-regulatory regions than in protein-coding regions. READ MORE
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3. Human leukocyte antigen in sickness and in health : Ankylosing spondylitis and HLA in Sweden
Abstract : The human leukocyte antigen (HLA) plays a major role in keeping us healthy, but some of the HLA alleles can contribute to disease susceptibility. One example is HLA-B*27, which confers increased susceptibility of ankylosing spondylitis and represents one of the strongest genetic associations found in any common human disease. READ MORE
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4. Detecting Signatures of Selection within the Dog Genome
Abstract : Deciphering the genetic basis of phenotypic diversity is one of the central aims of biological research. Domestic animals provide a unique opportunity for making substantial progress towards this goal. READ MORE