Search for dissertations about: "Mauno Vihinen"

Found 3 swedish dissertations containing the words Mauno Vihinen.

  1. 1. On protein structure, function and modularity from an evolutionary perspective

    Author : Robert Pilstål; Björn Wallner; Maria Sunnerhagen; Mauno Vihinen; Linköpings universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; bioinformatics; structure; biology; intrinsical; disorder; protein; sequence; evolution; mutation; epistasis; function; allostery; dynamics; simulation; prediction; graph; network; bioinformatik; struktur; biologi; strukturbiologi; intrinsiellt; oordnad; protein; sekvens; evolution; mutation; epistasis; funktion; allosteri; dynamik; simulation; prediktion; graf; nätverk;

    Abstract : We are compounded entities, given life by a complex molecular machinery. When studying these molecules we have to make sense of a diverse set of dynamical nanostructures with wast and intricate patterns of interactions. READ MORE

  2. 2. Bioinformatics Methods for Topology Prediction of Membrane Proteins

    Author : Konstantinos Tsirigos; Arne Elofsson; Mauno Vihinen; Stockholms universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Biochemistry towards Bioinformatics; biokemi med inriktning mot bioinformatik;

    Abstract : Membrane proteins are key elements of the cell since they are associated with a variety of very important biological functions crucial to its survival. They are implicated in cellular recognition and adhesion, act as molecular receptors, transport substrates through membranes and exhibit specific enzymatic activity. READ MORE

  3. 3. Biomarkers for Diagnosis, Therapy and Prognosis in Colorectal Cancer : a study from databases, machine learning predictions to laboratory confirmations

    Author : Xueli Zhang; Hong Zhang; Xiao-Feng Sun; Dirk Repsilber; Bairong Shen; Mauno Vihinen; Örebro universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biomarkers; diagnosis; therapy response; prognosis; database; machine learning; CRC;

    Abstract : Colorectal cancer (CRC) is one of the leading causes of cancer death worldwide. Early diagnosis and better therapy response have been believed to be associated with better prognosis. CRC biomarkers are considered as precise indicators for the early diagnosis and better therapy response. READ MORE