Search for dissertations about: "Medical Biochemistry"

Showing result 16 - 20 of 454 swedish dissertations containing the words Medical Biochemistry.

2. 16. Tumor Stroma in Anaplastic Thyroid Carcinoma : Interstitial Collagen and Tumor Interstitial Fluid Pressure

   Author : Ellen Lammerts; Lucio Nitsch; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; Collagen I synthesis; Fibrosis; Tumor - stroma interactions; PDGF; TGF-β; Inhibitor; Cell cycle; Tumor growth; Hyaluronan; Biokemi; Biochemistry; Biokemi; Medical Biochemistry; medicinsk biokemi;

   Abstract : Anaplastic thyroid carcinoma (ATC) is an aggressive malignancy in man with stromal fibrosis as one of the main features. Carcinoma cells synthesized no or little collagen I protein. READ MORE

4. 17. Neural Stem and Progenitor Cells : Cellular Responses to Known and Novel Factors

   Author : Jimmy Larsson; Karin Forsberg-Nilsson; Ola Hermanson; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neural stem cell; differentiation; proliferation; migration; PDGF; SCF; NRBP2; medulloblastoma; Biochemistry; Biokemi; Medical Biochemistry; Medicinsk biokemi;

   Abstract : Neural stem cell self-renewal and differentiation are tightly regulated events during CNS development, leading to cell division into new neural stem cells or the formation of neurons and glial cells. This thesis focuses on the cellular responses induced by known and novel factors in neural stem and progenitor cells (NSPCs). READ MORE

5. 18. The role of 1-intergrins in skeletal muscle differentiation and extracellular matrix assembly

   Author : Lars Lohikangas; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; β1 Integrins; Matrix Deposition; Skeletal Muscle Cell; Biokemi; Biochemistry; Biokemi; Medical Biochemistry; medicinsk biokemi;

   Abstract : Integrin subunit β1 forms heterodimeric receptors with at least 12 different α-subunits.These integrins are the main cellular receptors for extracellular matrix and they arenecessary for normal development. In this thesis, the effects of lack of integrin subunitβ1 on matrix deposition and on skeletal muscle development were studied. READ MORE

6. 19. Extracellular matrix as a regulator of cell behavior : Biological effects of hyaluronan biosynthesis and catabolism

   Author : Mehdi Rahmanian; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; Hyaluronan; hyaluronidase; CD44; Biokemi; Biochemistry; Biokemi; Medical Biochemistry; medicinsk biokemi;

   Abstract : Extracellular matrix surrounding cells is an important regulator of cellular functions. Hyaluronan (HA) is a glycosaminoglyean and a constituent component of the extracellular matrix in all tissues. It is synthesized by hyaluronan syntheses (HAS) at the inner surface of cell membrane and degraded by hyaluronidases to small fragments. READ MORE

7. 20. Novel chemical and enzymatic routes to the generation of heparin- related polysaccarides

   Author : Jianhui Rong; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; heparin; heparan sulphate; biosynthesis; 2-O-sulphotransferase; neo-glycosaminoglycan; conjugation; Biokemi; Biochemistry; Biokemi; Medical Biochemistry; medicinsk biokemi;

   Abstract : Heparin and heparan sulphate (HS) are structurally related polysaccharides influencing various biological processes. The biological functions of heparin/HS largely depend on interactions between the negatively charged polysaccharide chains and a variety of proteins. READ MORE