Search for dissertations about: "Medical Biotechnology Biomedical Laboratory Science Technology"

Showing result 1 - 5 of 115 swedish dissertations containing the words Medical Biotechnology Biomedical Laboratory Science Technology.

  1. 1. Microfluidic Compartmentalization for Smart Materials, Medical Diagnostics and Cell Therapy

    Author : Emre Iseri; Wouter van der Wijngaart; Nicole Pamme; KTH; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Microfluidics; microfabrication; compartmentalization; partitioning; droplet microfluidics; self-assembly; 3D microarrays; soft composites; beads; particles; core-shell particle; point-of-care; diagnostics; dipstick; digital bioassays; lab-on-a-chip; urinary tract infection; bacteria detection; E. coli; cell encapsulation; hydrogel; cell therapy; spider silk; magnetic metamaterials.; Mikrofluidik; mikrotillverkning; kompartmentalisering; partitionering; droppmikrofluidik; självmontering; 3D-mikromatriser; mjuka kompositer; pärlor; partiklar; kärna-skalpartikel; vårdpunkt; diagnostik; mätsticka; digitala bioanalyser; laboration-a-chip; urinvägsinfektion; bakteriedetektering; E. coli; cellinkapsling; hydrogel; cellterapi; spindelsilke; magnetiska metamaterial.;

    Abstract : The organisation of fluids in small compartments is ubiquitous in nature, such as in the cellular composition of all life. This work explores several engineering avenues where microscale fluid compartmentalization can bring novel material properties or novel functionality in life sciences or medicine. READ MORE

  2. 2. Assessment of microvascular and metabolic responses in the skin

    Author : Fredrik Iredahl; Erik Tesselaar; Folke Sjöberg; Simon Farnebo; Sven Andersson; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : The general aim of this project was to develop experimental in vivo models that allow for minimally invasive investigations of responses in the skin to microvascular and metabolic provocations. The cutaneous microvasculature has emerged as a valuable model and been proposed to mirror the microcirculation in other organs. READ MORE

  3. 3. Design of solid dosage forms for mucosal vaccination - Investigations on the influence of excipients on product performance

    Author : Annika Borde; Chalmers tekniska högskola; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; hydrophilic matrix tablets; osmotic pressure; protein release; freeze-drying; Vibrio cholerae; mucoadhesion; Bradford Assay; sublingual vaccine tablet; mucosal vaccination;

    Abstract : Most vaccines today are liquid formulations for parental administration. However, there are several drawbacks connected to these vaccines. Since injectable vaccines only induce systemic antibody responses, they are not effective against the various pathogens that affect mucosal surfaces with poor permeability for serum-derived antibodies, e.g. READ MORE

  4. 4. Development of Techniques for Characterization, Detection and Protein Profiling of Extracellular Vesicles

    Author : Sara Cavallaro; Jan Linnros; Apurba Dev; Hakho Lee; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; extracellular vesicles; streaming current; fluorescence microscopy; atomic force microscopy; scanning electron microscopy; protein profiling; size profiling; Biological and Biomedical Physics; Biologisk och biomedicinsk fysik;

    Abstract : Nanosized extracellular vesicles (EVs, ∼30-2000 nm) have emerged as important mediators of intercellular communication, offering opportunities for both diagnostics and therapeutics. In particular, small EVs generated from the endolysosomal pathway (∼30-150 nm), referred to as exosomes, have attracted interest as a suitable biomarker for cancer diagnostics and treatment monitoring based on minimally invasive liquid biopsies. READ MORE

  5. 5. Extracellular Matrix Based Materials for Tissue Engineering

    Author : Cecilia Aulin; Jöns Hilborn; Tim Bowden; Laura Creemers; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Extracellular matrix; collagen synthesis; bioreactor; cell culture; bone morphogenetic protein-2; noggin; hyaluronan; cartilage; Medical technology; Medicinsk teknik; Molecular biology; Molekylärbiologi; Orthopaedics; Ortopedi; Transplantation surgery; Transplantationskirurgi; Biomaterials; Biomaterial; Morphology; cell biology; pathology; Morfologi; cellbiologi; patologi; Cell and molecular biology; Cell- och molekylärbiologi; Polymer chemistry; Polymerkemi; Materials chemistry; Materialkemi; cellforskning; Cell Research; materialvetenskap; Materials Science; medicinsk cellbiologi; Medical Cell Biology; ortopedi; Orthopaedics;

    Abstract : The extracellular matrix is (ECM) is a network of large, structural proteins and polysaccharides, important for cellular behavior, tissue development and maintenance. Present thesis describes work exploring ECM as scaffolds for tissue engineering by manipulating cells cultured in vitro or by influencing ECM expression in vivo. READ MORE