Search for dissertations about: "Medical record linkage"

Showing result 1 - 5 of 62 swedish dissertations containing the words Medical record linkage.

  2. 1. Mitochondrial and chromosomal genomics in type 2 diabetes

    Author : Avinash Abhyankar; Genetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adaptive evolution; nuclear-mitochondrial interaction; linkage analysis; QTL; phylogenetic analysis; congenic; type 2 diabetes; GK rat;

    Abstract : Understanding the mechanisms of complex polygenic diseases like type 2 diabetes (T2D) is as complex as their nature. Cellular processes involved in glucose homeostasis need high and reliable energy supply. Mitochondria are the major energy producers in mammalian cells. READ MORE

  4. 2. Identification of Arthritis Regulating Genes in Rats

    Author : Peter Olofsson; Immunologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunologi; serologi; transplantation; Clinical genetics; Klinisk genetik; serology; Immunology; QTL; RA; Epistasis; Ncf1; Linkage; PIA; Arthritis; Rat;

    Abstract : The immune response is designed to protect the body from harmful microbial invasions. However, when the immune system attacks itself instead, an autoimmune reaction starts that damage our own cells, tissues and organs. READ MORE

  5. 3. On the effects of Streptococcal NAD+-glycohydrolase and Streptolysin O on macrophages

    Author : Elsa Westerlund; Värd-patogeninteraktioner; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Innate immunity; macrophage; Streptococcus pyogenes; IL-1beta; Nad -glycohydrolase;

    Abstract : SummaryThe human pathogen Streptococcus pyogenes (GAS) causes both superficial infections, such as strep throat, and invasive infections, such as necrotizing fasciitis, and is responsible for about half a million deaths each year. The number of GAS infections have increased since the 1980’s, due to the emergence of a M1T1 strain that has become widely disseminated. READ MORE

  6. 4. Genetic Factors and Nasal Tolerance in Rat Models for Rheumatoid Arthritis

    Author : Shemin Lu; Immunologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; nasal tolerance; linkage analysis; MHC; genetics; pristane induced arthritis; rheumatoid arthritis; collagen induced arthritis; Immunology; serology; transplantation; Immunologi; serologi;

    Abstract : We used three animal models of rats for rheumatoid arthritis (RA) in this study. Firstly, We found that CXI induced arthritis (CXIIA) is associated with the RT1 f haplotype and follows a chronic disease course affecting peripheral joints with both progression and relapses. READ MORE

  7. 5. Diagnostic Evaluation of Schizophrenia for Genetic Studies

    Author : Birgit Ekholm; Rolf Adolfsson; Erik Jönsson; Göran Sedvall; Leif Lindström; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Psychiatry; Schizophrenia; Diagnostic evaluation; Molecular genetic studies; Linkage; Association; Psykiatri; Psychiatry; Psykiatri; psykiatri; Psychiatry;

    Abstract : Schizophrenia is one of the most severe mental disorders. Heredity is accepted as a major causative factor. To find molecular mechanisms behind schizophrenia, patient materials with reliable and valid diagnoses must be identified. READ MORE