Search for dissertations about: "Medical record linkage"

Showing result 6 - 10 of 62 swedish dissertations containing the words Medical record linkage.

  2. 6. Search for Type 2 Diabetes Susceptibility Genes Using Multiple Approaches

    Author : Cecilia Lindgren; Malmö Institutionen för kliniska vetenskaper; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; single nucleotide polymorphism SNP ; transmission-disequilibrium test TDT ; genetic variation; single strand conformational polymorphism SSCP ; gene expression; insulin; glucose; genome-wide scan; linkage; genetic association; Type 2 diabetes; early onset diabetes EOD ; sekretion; diabetologi; Endokrinologi; diabetology; Endocrinology; secreting systems; signal-to-noise ratio SNR ;

    Abstract : Type 2 diabetes mellitus is a multifactorial disorder characterized by chronic hyperglycemia resulting from pancreatic dysfunction and insulin resistance. It is a common disorder with a complex pattern of inheritance, likely to reflect the influence of multiple genetic and environmental factors on the diabetes risk. READ MORE

  4. 7. A search for genes influencing autoimmunity - focus on rheumatoid arthritis and multiple sclerosis

    Author : Johan Jirholt; Immunologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; autoimmunity genetics eae cia linkage; cytogenetics; Genetics; cytogenetik; Genetik;

    Abstract : The causes of autoimmune diseases are largely unknown today, but there is evidence supporting a substantial complex genetic influence on many of these diseases as well as environmental factors and chance. In this thesis I have tried to get one step closer to the genetic causes of two autoimmune diseases through their induced counterparts in mice, namely rheumatoid arthritis (RA) and multiple sclerosis (MS). READ MORE

  5. 8. Specifity and genetic control of B cell reactivity in experimental arthritis

    Author : Patrik Wernhoff; Immunologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; serologi; transplantation; Genetics; cytogenetics; Genetik; cytogenetik; Immunologi; Autoimmunity B-cell response Epitope Genetics Linkage Analysis; Immunology; serology;

    Abstract : Collagen-induced arthritis (CIA) and pristane-induced arthritis (PIA) are animal models for human rheumatoid arthritis (RA), and can be induced in susceptible mouse and rat strains. CIA is induced by immunization of type II collagen (CII), a cartilage specific protein together with Freund’s adjuvant. READ MORE

  6. 9. T cells, Cytokines, and Genetic Factors in Autoimmunity Studies of experimental models of arthritis and sialadenitis

    Author : Åsa Johansson; Immunologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; rheumatology locomotion; Collagen-induced arthritis Sialadenitis Mice Knockout Linkage analysis T cells Cytokines; muscle system; Skeleton; reumatologi; muskelsystem; Skelett;

    Abstract : To understand the pathogenesis of autoimmune diseases we have to consider the problem from different angles. Animal models provide a tool to further understand these complex diseases, as the influence of genetic and environmental factors could be limited. READ MORE

  7. 10. Targeting Non-obvious Errors in Death Certificates

    Author : Lars Age Johansson; Ragnar Westerling; Eric Jougla; Uppsala universitet; []
    Keywords : Social medicine; Cause of death; Death certificates; Medical records; Mortality statistics; Quality control; Medical record linkage; Socialmedicin;

    Abstract : Mortality statistics are much used although their accuracy is often questioned. Producers of mortality statistics check for errors in death certification but current methods only capture obvious mistakes. This thesis investigates whether non-obvious errors can be found by linking death certificates to hospital discharge data. READ MORE