Search for dissertations about: "Medicin människa och djur Genetics Medicine human and vertebrates platelet single nucleotide polymorphism myocardial infarction stent G-protein coupled receptor P2Y cytogenetics Genetik cytogenetik Cardiovascular system Kardiovaskulära systemet"

Found 1 swedish dissertation containing the words Medicin människa och djur Genetics Medicine human and vertebrates platelet single nucleotide polymorphism myocardial infarction stent G-protein coupled receptor P2Y cytogenetics Genetik cytogenetik Cardiovascular system Kardiovaskulära systemet.

  2. 1. Genetic studies on cardiovascular disease - identification of novel drug targets

    Author : Stefan Amisten; Kardiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; Medicin människa och djur ; Medicine human and vertebrates ; platelet; single nucleotide polymorphism; myocardial infarction; stent; G-protein coupled receptor; P2Y; cytogenetics; Genetik; cytogenetik; Cardiovascular system; Kardiovaskulära systemet;

    Abstract : The aim of this thesis was to identify novel potential drug targets of cardiovascular disease with a focus on G-protein coupled receptors. We identified a common genetic variant of the ATP receptor P2Y11, where an alanine is substituted with a threonine at position 87 of the P2Y11 receptor that increases the risk of developing acute myocardial infarction. READ MORE