Search for dissertations about: "Medicin och hälsovetenskap Medicinska grundvetenskaper Medicinsk genetik"
Showing result 11 - 15 of 312 swedish dissertations containing the words Medicin och hälsovetenskap Medicinska grundvetenskaper Medicinsk genetik.
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11. Epigenetic changes and immunological features of chronic obstructive pulmonary disease
Abstract : Background: Chronic obstructive pulmonary disease (COPD) is a heterogenous and chronic inflammatory syndrome with the lungs as its main target organ. Clinically, COPD is characterized by airflow limitation, chronic respiratory symptoms, and many extrapulmonary comorbidities. READ MORE
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12. PARN - A Tale of A de-Tailor : Functional importance of poly(A) degradation in developmental and telomere biology disorders
Abstract : Poly(A)-specific ribonuclease (PARN) is a eukaryotic 3’-5’exoribonuclease that removes poly(A) tails of many coding and non-coding RNAs. In this thesis, we have studied the physiological role of PARN. READ MORE
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13. Human Adipocytes : Proteomic Approaches
Abstract : Type 2 diabetes is characterized by increased levels of glucose in the blood originating from insulin resistance in insulin sensitive tissues and from reduced pancreatic insulin production. Around 400 million people in the world are diagnosed with type 2 diabetes and the correlation with obesity is strong. READ MORE
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14. Functional organisation of the cell nucleus in the fission yeast, Schizosaccharomyces pombe
Abstract : In eukaryotes the genome adopts a non-random spatial organisation, which is important for gene regulation. However, very little is known about the driving forces behind nuclear organisation. READ MORE
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15. Genetics, epigenetics and functional mechanisms in inherited corneal and retinal dystrophies
Abstract : Inherited eye disorders (IED) are groups of genetically and clinically heterogenous conditions affecting different tissues in the eye. IED are most often progressive with reduced vision or legal blindness as outcome. READ MORE