Search for dissertations about: "Medicinsk mikrobiologi"

Showing result 1 - 5 of 520 swedish dissertations containing the words Medicinsk mikrobiologi.

  1. 1. Novel diagnostic microarray assay formats towards comprehensive on-site analysis

    Author : Jesper Gantelius; Helene Andersson-Svahn; Christer Wingren; KTH; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; NATURVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; NATURAL SCIENCES; MEDICAL AND HEALTH SCIENCES; magnetic microbeads; gold nanobeads; microarrays; lateral flow; on-site diagnosis; SNPs; pestivirus; autoimmunity; contagious bovine pleuropneumonia; comsol multiphysics; finite element method; Microbiology; Mikrobiologi; Biochemistry; Biokemi;

    Abstract : Advances in molecular methods for analyzing DNA, RNA and proteins in humans as well as in other animals, plants, fungi, bacteria or viruses have greatly increased the resolution with which we can study life’s complexity and dynamics on earth. While genomic, transcriptomic and proteomic laboratory tools for molecular diagnosis of disease are rapidly becoming more comprehensive, the access to such advanced yet often expensive and centralized procedures is limited. READ MORE

  2. 2. The Role of Microvascular Pericytes in the Generation of Pro-fibrotic Connective Tissue Cells : Investigations in vitro and in Reactive Tissues in vivo

    Author : Jakob Karén; Christian Sundberg; Gunilla Westergren-Thorsson; Uppsala universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICAL AND HEALTH SCIENCES; pericyte fibroblast differentiation fibrosis; Biochemistry; Biokemi; Microbiology; Mikrobiologi; Cell biology; Cellbiologi; Medical Biochemistry; Medicinsk biokemi; Cellforskning; Cell Research; Mikrobiologi; Microbiology;

    Abstract : Pericytes are cells of mesenchymal origin located on the abluminal side, juxtapositioned to the endothelial cells in capillaries, venules and small arterioles. They are important for maintaining vessel integrity in resting tissues as well as the formation and stabilization of new vessels. READ MORE

  3. 3. Functional characterization of the human adenovirus pVII protein and non-coding VA RNAI

    Author : Raviteja Inturi; Tanel Punga; Goran Akusjarvi; Thomas Dobner; Uppsala universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICAL AND HEALTH SCIENCES; Adenovirus; VA RNA; protein VII; Ubiquitination; proteasome; anti-viral; Medical Biochemistry; Medicinsk biokemi; Mikrobiologi; Microbiology; Medical Virology; Medicinsk virologi;

    Abstract : Human adenovirus (HAdV) is a common pathogen causing a broad spectrum of diseases. HAdV encodes the pVII protein, which is involved in nuclear delivery, protection and expression of viral DNA. To suppress the cellular interferon (IFN) and RNA interference (RNAi) systems, HAdVs encode non-coding virus-associated (VA) RNAs. READ MORE

  4. 4. Methods development for metaproteomics-guided bioprospecting of novel enzymes

    Author : Jutta Speda; Martin Karlsson; Nalle Jonsson; Antonius Van Maris; Linköpings universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; NATURVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; NATURAL SCIENCES; MEDICAL AND HEALTH SCIENCES;

    Abstract : Industrial biotechnology has been announced by several organizations and governments as a key enabling technology for the enhanced economic growth in a low-carbon and knowledge-based bioeconomy. An important goal to promote an environment friendly and sustainable industrial biotechnology is the discovery of new enzymes. READ MORE

  5. 5. The discovery of antiviral compounds targeting adenovirus and herpes simplex virus : assessment of synthetic compounds and natural products

    Author : Mårten Strand; Göran Wadell; Mikael Elofsson; Ya-Fang Mei; Lieve Naesens; Umeå universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; NATURAL SCIENCES; MEDICAL AND HEALTH SCIENCES; virology; antiviral; adenovirus; herpes simplex virus; small molecule; inhibitor; hsv; drug discovery; medicinsk virologi; Medical Virology; datorlingvistik; computational linguistics; mikrobiologi; Microbiology;

    Abstract : There is a need for new antiviral drugs. Especially for the treatment of adenovirus infections, since no approved anti-adenoviral drugs are available. Adenovirus infections in healthy persons are most often associated with respiratory disease, diarrhea and infections of the eye. These infections can be severe, but are most often self-limiting. READ MORE