Search for dissertations about: "Medulloblastoma"

Showing result 11 - 15 of 45 swedish dissertations containing the word Medulloblastoma.

  2. 11. Regulation of the platelet-derived growth factor β-receptor

    Author : Catrin Molander; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PDGF; inflammation; TNF-a; tyrosine kinase; medulloblastoma; Myc; NF-Y; Sp1;

    Abstract : Growth factors are important signalling molecules, regulating cell growth, as well as cell movement, differentiation and apoptosis. They bind to specific receptors on the cell surface causing activation of the receptors. Activated receptors then attract adaptor molecules that brings the signal further into the cell. READ MORE

  4. 12. Neural Stem and Progenitor Cells : Cellular Responses to Known and Novel Factors

    Author : Jimmy Larsson; Karin Forsberg-Nilsson; Ola Hermanson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neural stem cell; differentiation; proliferation; migration; PDGF; SCF; NRBP2; medulloblastoma; Biochemistry; Biokemi; Medical Biochemistry; Medicinsk biokemi;

    Abstract : Neural stem cell self-renewal and differentiation are tightly regulated events during CNS development, leading to cell division into new neural stem cells or the formation of neurons and glial cells. This thesis focuses on the cellular responses induced by known and novel factors in neural stem and progenitor cells (NSPCs). READ MORE

  5. 13. Characterizing and modulating the effects of ionizing radiation to the juvenile hippocampus

    Author : Malin Blomstrand; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; low-dose radiation; CNS; hippocampus; apoptosis; cytokines; growth factors; microglia; medulloblastoma; hippocampal sparing; tumor bed boost; cognitive risk estimation;

    Abstract : Survival rates after childhood cancer treatment have improved, leading to a growing population of survivors. Radiotherapy is an important tool for curing cancer in the brain. Unfortunately, radiotherapy is associated with late side effects e.g. READ MORE

  6. 14. Graph theory based approaches for gene prioritization in biological networks : Application to cancer gene detection in medulloblastoma

    Author : Hrafn Holger Weishaupt; Sergei Silvestrov; Erik Bongcam-Rudloff; Mälardalens högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Mathematics Applied Mathematics; matematik tillämpad matematik;

    Abstract : Networks provide an intuitive and highly adaptable means to model relationships between objects. When translated to mathematical graphs, they become further amenable to a plethora of mathematical operations that allow a detailed study of the underlying relational data. READ MORE

  7. 15. New potential targets in medulloblastoma therapy : studies on cellular mechanisms and mediators

    Author : Ninib Baryawno; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Medulloblastoma is an embryonal tumour that mainly affects children. It is the most common malignant brain tumour in children and accounts for 15% of all childhood brain tumours. It most often presents in the cerebellum and is considered to be a disorder of normal development. READ MORE