Search for dissertations about: "Medulloblastoma"
Showing result 16 - 20 of 45 swedish dissertations containing the word Medulloblastoma.
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16. Elucidating the role of DNA damage and human cytomegalovirus in medulloblastoma and glioblastoma
Abstract : The most common primary malignant brain tumor in children is Medulloblastoma, while Glioblastoma is the most common in adults. Treatment for both include some combination of surgery, radiation therapy, and chemotherapy. READ MORE
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17. Understanding and targeting the architecture in cancer : novel therapies in neuroblastoma and medulloblastoma
Abstract : Cancer is the second leading cause of death worldwide after cardiovascular diseases. In Sweden, childhood cancer is the most common cause of death in children 1-14 years of age. Owing to advances in treatment and a better understanding of tumor biology, survival rates have increased to over 80% in most Western countries. READ MORE
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18. Experimental combination therapy of brain cancer cell models
Abstract : Epigenetic alterations and aberrant expression of genes controlling epigenetic mechanisms have been identified in several cancers, including medulloblastoma and glioma, the most common primary brain tumors in children and adults, respectively. We have been investigating if combination therapy using histone deacetylase inhibitors (HDACi) and receptor tyrosine kinase inhibitors (RTKi) will enhance glioblastoma and medulloblastoma cell killing. READ MORE
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19. Mechanisms acting on Hedgehog-GLI pathway and their therapeutic potential
Abstract : Hedgehog signaling is crucial for diverse aspects of animal development, essential in regulating many cellular processes and is largely implicated in various forms of human cancer. However, many aspects of Hedgehog signaling are not completely understood. READ MORE
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20. Omega-3 fatty acids in the treatment of childhood cancer
Abstract : Childhood cancer is the primary cause of deaths among Swedish children. Advances in treatment regimens have improved cure rate considerably in the latest decades. READ MORE