Search for dissertations about: "Mefloquine"
Showing result 1 - 5 of 10 swedish dissertations containing the word Mefloquine.
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1. Induction of Mast Cell Apoptosis via Granule Permeabilization : A Novel Approach to Target Mast Cells
Abstract : Mast cells are densely granulated tissue-resident immune cells that play an important role in orchestrating inflammatory responses. Dysregulated increases in the numbers and activation status of mast cells can have deleterious consequences for the body in various inflammatory diseases. READ MORE
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2. Development of Analytical Methods for the Determination of Antimalarials in Biological Fluids
Abstract : The aim of this thesis was to develop analytical methods for measuring antimalarial drugs in biological fluids. Solid phase extraction (SPE) was used for the enrichment and purification of the drugs. READ MORE
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3. Determination of Mefloquine Enantiomers and their Main Metabolite in Biological Fluids
Abstract : .... READ MORE
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4. Enantioseparation of drugs and related compounds using chiral mobile phase additives
Abstract : Neutral and anionic chiral mobile phase additives have been employed to separate enantiomers of drugs and related compounds using aqueous buffer solution and hydro-organic solvent mixtures as mobile phases.Ester derivatives of tartaric acid, e. g. READ MORE
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5. Experimental pharmacodynamic and kinetic studies related to new combination therapies against P. falciparum malaria
Abstract : Artemisinin (ART) class of compounds are of special interest due to their rapid onset of action and high activity against multidrug resistant malaria. The major drawback in monotherapy with ART and its derivatives is the high rate of recrudescent infection. READ MORE