Search for dissertations about: "Meiqiongzi Zhang"

Found 1 swedish dissertation containing the words Meiqiongzi Zhang.

2. 1. Making sense from nonsense and missense : pharmacological rescue of mutant tumor suppressor p53

   Author : Meiqiongzi Zhang; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : A large fraction of human tumors carry inactivating mutations in the TP53 tumor suppressor gene. Approximately 75% of these mutations are missense mutations and around 10% are nonsense mutations. TP53 inactivation allows evasion of cell death and rapid tumor progression. READ MORE