Search for dissertations about: "Membrane Proteins chemistry"

Showing result 1 - 5 of 100 swedish dissertations containing the words Membrane Proteins chemistry.

2. 1. On methods for probing structure and function of membrane proteins

   Author : Erik Jansson; Chalmers tekniska högskola; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; proteomics; patch-clamp; mass spectrometry.; proteoliposomes; microfluidic superfusion; cholesterol; TRPV1; limited proteolysis; Membrane proteins; fluorescence;

   Abstract : The determination of structure–function relationships in membrane proteins plays a key role for the understanding of molecular mechanisms in biological systems, and may provide information on how these systems can be modulated by pharmaceuticals. The aim of the work described herein was to develop methods for studying structure and function of membrane proteins, ideally in combination. READ MORE

4. 2. Strategies to explore the membrane proteome of a cell

   Author : Gianluca Maddalo; Leopold L. Ilag; Peter James; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Membrane proteins; Proteomics; Escherichia coli; Enterococcus faecalis; Synechocystis; Mass Spectrometry; BN SDS-PAGE; FT-ICR-MS; Myelin P2 protein; Analytical chemistry; Analytisk kemi; Analytical Chemistry; analytisk kemi;

   Abstract : The cell envelope plays key roles in numerous processes such as maintaining cellular integrity, communication with other cells, signal transduction, maintenance of cellular homeostasis, and regulation of the traffic of molecules between the cell and the extracellular milieu. Essential membrane components in many of these processes are proteins. READ MORE

5. 3. Into the Membrane and Beyond : Improving Membrane Protein Over-Expression in Escherichia coli

   Author : Mirjam Klepsch; Jan-Willem de Gier; Reinhard Grisshammer; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Escherichia coli; membrane protein over-expression; proteomics; T7 RNA polymerase; peptide transport; strain engineering; Biochemistry; Biokemi; Biophysical chemistry; Biofysikalisk kemi; biokemi; Biochemistry;

   Abstract : Membrane proteins fulfil a wide variety of essential functions in the cell and many are (potential) drug targets. Since their natural abundance is usually very low, most membrane proteins have to be over-expressed for functional and structural studies. READ MORE

6. 4. Interaction of Calcium Ions with Lipid Membranes

   Author : Baharan Ali Doosti; Chalmers tekniska högskola; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; phospholipid bilayer membrane; membrane dynamics; micromanipulation; calcium ions; cell migration.; membrane nanotube; membrane tubular protrusions; calcium ion concentration gradient; membrane bending; giant unilamellar vesicle;

   Abstract : Bilayer membranes enclose and shield the biological cell and its inner compartments, as well as the tubular networks that exist within and between the cells. Due to their fluidic nature, the membranes are incredibly dynamic and flexible, which allows them to bend, reshape and fuse in response to mechanical and chemical stimuli within their natural microenvironments. READ MORE

7. 5. Topology Prediction of Membrane Proteins: Why, How and When?

   Author : Karin Melén; Gunnar von Heijne; Hugh Salter; Janet Thornton; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; membrane protein; topology prediction; bioinformatics; Theoretical chemistry; Teoretisk kemi; biokemi; Biochemistry;

   Abstract : Membrane proteins are of broad interest since they constitute a large fraction of the proteome in all organisms, up to 20-30%. They play a crucial role in many cellular processes mediating information flow and molecular transport across otherwise nearly impermeable membranes. READ MORE