Search for dissertations about: "Meprinβ"

Found 1 swedish dissertation containing the word Meprinβ.

2. 1. The amyloid-β precursor protein (APP) and its adaptor protein Fe65 : Two key players in Alzheimer’s disease

   Author : Preeti Menon; Anna-Lena Ström; Thorsten Müller; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alzheimer s disease; APP; Fe65; Meprinβ; α-secretase; APP processing; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

   Abstract : Alzheimer’s disease (AD) is a neurodegenerative disease characterized by the abnormal accumulation and aggregation of amyloid beta (Aβ) peptides within the brain. Generation of Aβ occur when the amyloid-beta precursor protein (APP) is proteolytically processed by β- and then γ-secretase in the amyloidogenic pathway. READ MORE