Search for dissertations about: "Metaboliska modeller"

Found 4 swedish dissertations containing the words Metaboliska modeller.

  1. 1. Adaptations and constraints associated with autotrophy in microbial metabolism

    Author : Johannes Asplund Samuelsson; Elton P. Hudson; Adil Mardinoglu; Costas D. Maranas; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Autotrophy; Carbon fixation; CO2 fixation; Calvin cycle; CBB cycle; Bacteria; Archaea; Prokaryotes; Cyanobacteria; Synechocystis; E. coli; Comparative genomics; Metabolic engineering; Microbial metabolism; Machine learning; Systems biology; Ribosome profiling; Kinetic modeling; Enzyme kinetics; Metabolic models; Pathway enumeration; Biosynthesis pathways; Metabolomics; Metabolite concentrations; Thermodynamics; Autotrofi; Kolfixering; CO2-fixering; Calvincykeln; CBB-cykeln; Bakterier; Arkéer; Prokaryoter; Cyanobakterier; Synechocystis; E. coli; Jämförande genomik; Metabolisk ingenjörskonst; Mikrobiell metabolism; Maskininlärning; Systembiologi; Ribosomprofilering; Kinetisk modellering; Enzymkinetik; Metaboliska modeller; Syntesvägsuppräkning; Biosyntesvägar; Metabolomik; Metabolitkoncentrationer; Termodynamik; Bioteknologi; Biotechnology;

    Abstract : Carbon dioxide (CO2) emissions from human activities are driving climate change, but the pending crisis could be mitigated by a circular carbon economy where released CO2 is recycled into commodity chemicals. Autotrophic microbes can make a contribution by producing chemicals, such as biofuels, from CO2 and renewable energy. READ MORE

  2. 2. Bioenergetic and Mechanical Modeling of Endurance Sports with Emphasis on Individualization

    Author : Julius Lidar; Mikael Bäckström; Mats Ainegren; David Sundström; Dietmar Saupe; Mittuniversitetet; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY;

    Abstract : Endurance athletes strive to improve their race times by enhancing their physical abilities, techniques, tactics, and equipment. Numerical simulations can aid in this effort by enabling repeated testing under identical conditions, thus isolating the effect of a single variable of interest on race time. READ MORE

  3. 3. Macroscopic Modeling of Metabolic Reaction Networks and Dynamic Identification of Elementary Flux Modes by Column Generation

    Author : Hildur Æsa Oddsdóttir; Anders Forsgren; Bernhard Palsson; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Metabolic Network; Optimization; Robust Optimization; Least-squares; Column Generation; Modeling; Algorithm; Elementary Flux Mode; Metabolic Flux Analysis; Chinese Hamster Ovary Cell; Amino Acid Metabolism; Tillämpad matematik och beräkningsmatematik; Applied and Computational Mathematics;

    Abstract : In this work an intersection between optimization methods and animal cell culture modeling is considered. We present optimization based methods for analyzing and building models of cell culture; models that could be used when designing the environment cells are cultivated in, i.e., medium. READ MORE

  4. 4. Protein aggregation: Computational modeling and Monte Carlo algorithm development

    Author : Sigurdur Jonsson; Beräkningsbiologi och biologisk fysik - Genomgår omorganisation; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Monte Carlo simulations; protein aggregation; disordered proteins; Fysicumarkivet A:2014:Jonsson;

    Abstract : Although organisms have evolved sophisticated cellular mechanisms for regulating their various protein networks, proteins sometimes start to clump together in an uncontrolled way. The aggregation of proteins has been associated with a range of serious diseases. READ MORE