Search for dissertations about: "Metal binding"

Showing result 1 - 5 of 217 swedish dissertations containing the words Metal binding.

  2. 1. Metal Affinity Peptides in Biotechnological Applications As tools in protein purification, protein stabilisation, metal quantification and metal tolerance of bacteria and plants

    Author : Malin Mejàre; Tillämpad biokemi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; cadmium; metal quantification; fusion tag; metal affinity tag; phage display; peptide library; metal tolerance; metal resistance; metal accumulation; bioremediation; transgenic plant; tobacco; potato; protein purification; immobilised metal affinity chromatography; metal affinity precipitation; metal detection; protein stabilisation; Bioteknik; Biotechnology; Biokemi; Metabolism; Biochemistry; metal ion;

    Abstract : Metal affinity tags have been fused to proteins and demonstrated to function as tools in protein purification, protein stabilisation, quantitative metal analysis and metal tolerance of bacteria and plants. In biotechnological applications proteins frequently have to function in nonnatural environments with harsh conditions which impose requirements for high stability on the proteins. READ MORE

  4. 2. Structural and physicochemical studies on metal and porphyrin binding by the Bacillus subtilis ferrochelatase

    Author : Mattias Hansson; Biokemi och Strukturbiologi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; metal specificity; metal binding; porphyrin metallation; time resolved crystallography; fluorescence quenching; X-ray structure; inclusion bodies; Bacillus subtilis; heme biosynthesis; ferrochelatase; hemH;

    Abstract : The enzyme ferrochelatase (EC 4.99.1.1) is the terminal enzyme in the biosynthetic pathway of heme b and catalyzes the insertion of Fe(II) into protoporphyrin IX. READ MORE

  5. 3. To metal, or not to metal : Diverse mechanisms of O2-activation and radical storage in the ferritin superfamily

    Author : Vivek Srinivas; Martin Högbom; Brian Hoffman; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Metalloprotein; di-metal; Oxygen activation; Substrate oxidation; Ribonucleotide reductase; Radical; DOPA; ADE-DOT; X-Ray free-electron laser; soluble Methane monooxygenase; Biochemistry; biokemi;

    Abstract : Proteins in the Ferritin-like superfamily are characterized by a four alpha-helical structural motif. These proteins are distributed across all three kingdoms of life and perform a wide range of functions. READ MORE

  6. 4. Challenges in Computational Biochemistry: Solvation and Ligand Binding

    Author : Jens Carlsson; Johan Åqvist; Chris Reynolds; Uppsala universitet; []
    Keywords : Molecular biology; computer simulations; molecular dynamics; solvation free energy; Generalized-Born; Poisson-Boltzmann; ligand binding; binding free energy; linear interaction energy; binding entropy; hydration entropy; Molekylärbiologi;

    Abstract : Accurate calculations of free energies for molecular association and solvation are important for the understanding of biochemical processes, and are useful in many pharmaceutical applications. In this thesis, molecular dynamics (MD) simulations are used to calculate thermodynamic properties for solvation and ligand binding. READ MORE

  7. 5. Computational Studies of Metal Clusters and Carbon Nanotubes

    Author : Anders Börjesson; Högskolan i Borås; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; carbon nanotube; metal clusters; nanotubesmetal junction; melting temperatures; nanotechnology; molecular dynamics; monte carlo; tight binding; atomistic simulations; Energi och material;

    Abstract : Carbon nanotubes constitute a promising candidate material in the realisation of nanoscaled electronics. This requires the ability for systematic production of carbon nanotubes with certain properties. This is called selective carbon nanotube growth. READ MORE