Search for dissertations about: "Metastatic melanoma"
Showing result 1 - 5 of 67 swedish dissertations containing the words Metastatic melanoma.
-
1. Novel immunotherapies for metastatic melanoma - from mouse models towards clinical trials
Abstract : Immunotherapies including checkpoint blockade and adoptive T cell transfer (ACT) show great promise for the treatment of melanoma, with long-term effects in some patients. However, around half of the patients with metastatic malignant melanoma will not be cured with available therapies today, and these patients require other treatment strategies. READ MORE
-
2. Genomic analysis of primary and metastatic malignant melanoma
Abstract : “Cutaneous melanoma is a most unpredictable lesion” wrote Alexander Breslow in 1970. He was one of the first to predict outcome in melanoma patients, based on the thickness of the primary tumor, and today this parameter bears his name and remains the main prognostic factor in melanoma. READ MORE
-
3. Clinical aspects of molecular profiles in metastatic malignant melanoma
Abstract : Malignant melanoma is a heterogeneous, malignant neoplastic disease, most often originating in the skin. Melanoma is characterized by a high mutational load and has a vastly variable prognosis, depending on disease stage. READ MORE
-
4. Translational studies of metastatic melanoma in the era of immunotherapy - from humanized mouse models to clinical trials
Abstract : Immunotherapy with PD-1 inhibitors has transformed the treatment of met-astatic cutaneous mela- noma, and can lead to complete and durable responses in a proportion of patients. However, in around half of the patients, the treatment has little or no effect. READ MORE
-
5. Exploring the Molecular Landscape of Cutaneous Melanoma
Abstract : Cutaneous malignant melanoma (CMM) is one of the most aggressive skin malignancies with poor prognosisfor the patients with metastatic disease. Earlier studies have highlighted the existing molecular diversityamongst CMM tumors. READ MORE