Search for dissertations about: "MglA"
Found 4 swedish dissertations containing the word MglA.
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1. Mechanisms of the intracellular survival of Francisella tularensis
Abstract : Francisella tularensis is a gram-negative, highly virulent, intracellular bacterium which causes the zoonotic disease tularemia. The subspecies tularensis and holarctica are clinically important, and the former is the more virulent. The intracellular lifestyle of F. READ MORE
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2. The oxidative stress response of Francisella tularensis
Abstract : Francisella tularensis is capable of infecting numerous cell types, including professional phagocytes. Upon phagocytosis, F. tularensis resides within the phagosome before escaping into the cytosol to replicate. Phagocytes constitute a hostile environment rich in ROS, which are employed as a means of killing pathogens. READ MORE
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3. Effects of Francisella tularensis infection on macrophage intracellular signaling
Abstract : Microbes contain a number of structural components, also known as pathogen associated molecular patterns (PAMP), which can be recognized by the host defense system. The PAMP serve as ligands for Toll-like receptors (TLR) expressed on phagocytic cells. READ MORE
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4. Francisella tularensis infection induces macrophage cell death
Abstract : Francisella tularensis, the causative agent of tularemia, is a potent human and animal pathogen. Its principal survival mechanism is rapid intracellular multiplication. READ MORE