Search for dissertations about: "Mia Phillipson"
Showing result 1 - 5 of 15 swedish dissertations containing the words Mia Phillipson.
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1. Acid transport through gastric mucus : A study in vivo in rats and mice
Abstract : The gastric mucosa is frequently exposed to endogenously secreted hydrochloric acid of high acidity. Gastric mucosal defense mechanisms are arranged at different levels of the gastric mucosa and must work in unison to maintain its integrity. READ MORE
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2. Leukocytes in Angiogenesis : Learning from Transplanted Pancreatic Islets
Abstract : Angiogenesis, the growth of new blood vessels, is a complex process involving several cell types and molecular signals. Excessive vascular growth is a problem in tumors, and insufficient vascularization hampers the function of transplanted insulin-producing pancreatic islets. READ MORE
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3. Engraftment of Pancreatic Islets in Alternative Transplantation Sites and the Feasibility of in vivo Monitoring of Native and Transplanted Beta-Cell Mass
Abstract : Islet transplantation is a possible curative treatment for type 1 diabetes (T1D). Currently the liver dominates as implantation site, despite the many challenges encountered at this site.Acute hypoxia in islets transplanted to muscle and omentum, two possible alternative sites, was prevailing. READ MORE
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4. Auxiliary Cells for the Vascularization and Function of Endogenous and Transplanted Islets of Langerhans
Abstract : Type 1 diabetes develops through the progressive destruction of the insulin-producing beta-cells. Regeneration or replacement of beta-cells is therefore needed to restore normal glucose homeostasis. Presently, normoglycemia can be achieved by the transplantation of whole pancreas or isolated islets of Langerhans. READ MORE
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5. On macrophage contributions to tissue homeostasis : New insights on pancreas development and healing of ischemic injury
Abstract : Besides providing host defence against innumerable threats, macrophages display additional key functions for preservation of tissue homeostasis. This thesis includes four studies that explore novel macrophage functions in both the development of islets of Langerhans and healing of ischemic injury in mice. READ MORE