Search for dissertations about: "Mia Phillipson"

Showing result 6 - 10 of 15 swedish dissertations containing the words Mia Phillipson.

  2. 6. Functional characterization of pro-angiogenic neutrophils

    Author : Jalal Lomei; Mia Phillipson; Gustaf Christoffersson; Johan Kreuger; Lars Olaf Cardell; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; angiogenesis; leukocytes; neutrophils; pro-angiogenic neutrophils; islets transplantation; intravital microscopy; aortic ring assay; phagocytosis; ROS production; hypoxia; vascular permeability; neutrophil recruitment; Medical Cell Biology; Medicinsk cellbiologi;

    Abstract : The vascular system stretches throughout the body to provide oxygen, nutrition, and to remove waste products from cell metabolism. Angiogenesis, formation of new blood vessels by sprouting from pre-existing vessels, is one of the main mechanisms involved in blood vessel formation. READ MORE

  4. 7. Cancer Immunotherapy : Oncolytic viruses and CAR-T cells

    Author : Jing Ma; Di Yu; Magnus Essand; Mia Phillipson; Mohanraj Ramachandran; Karl-Johan Malmberg; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cancer immunotherapy; Oncolytic viruses; chimeric antigen receptor CAR -T cells; Helicobacter pylori Neutrophil Activating Protein;

    Abstract : Various forms of cancer immunotherapy have developed rapidly with improved survival and quality of life for cancer patients. Cancer immunotherapy aims to educate the patient’s immune system to eliminate cancer cells, including immune checkpoint inhibitors (ICIs), adoptive cell transfer (mostly T cells), oncolytic viruses (OVs) and cancer vaccines. READ MORE

  5. 8. A close-up on neutrophils : Visualizing the mechanisms of their in vivo recruitment and function

    Author : Sara Massena; Mia Phillipson; Randall S. Jonhson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; angiogenesis; chemokine; chemotactic gradient; citrullination; hypoxia; inflammation; intraluminal crawling; intravital imaging; PAD enzymes; permeability; proangiogenic; proinflammatory;

    Abstract : A successful immune response depends on prompt and sufficient recruitment of leukocytes from the circulation to infected or injured sites. Mobilization of leukocytes to hypoxic tissues is vital for angiogenesis, i.e. the formation of new blood vessels from preexisting vasculature, and thus crucial for tissue growth and regeneration. READ MORE

  6. 9. Macrophages and neutrophils in tissue homeostasis and recovery from ischemic injury

    Author : Kristel Parv; Mia Phillipson; Gustaf Christoffersson; Per-Ola Carlsson; Stephen Jenkins; Uppsala universitet; []
    Keywords : LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; macrophages; neutrophils; hindlimb ischemia; ischemic disease; mural cells; diabetes mellitus; postnatal β cell maturation.;

    Abstract : Neutrophils and macrophages have functions beyond protection against pathogens. The overall aim of the work presented in this thesis was to identify novel tasks for these innate immune cells in maintaining homeostasis. READ MORE

  7. 10. Nitrate, Nitrite and Nitric Oxide in Gastric Mucosal Defense

    Author : Joel Petersson; Lena Holm; Jon Lundberg; Mia Phillipson; Matthew Grisham; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; dietary nitrate; mucus gel layer; mucosal blood flow; mucus thickness; laser-Doppler flowmetry; mucosal damage; intra-vital microscopy; mucosal permeability; Physiology; Fysiologi;

    Abstract : The human stomach normally contains high levels of bioactive nitric oxide (NO). This NO derives from salivary nitrate (NO3-) that is converted to nitrite (NO2-) by oral bacteria and thereafter non-enzymatically reduced in the acidic gastric lumen to NO. READ MORE