Search for dissertations about: "Michael Alvarsson"

Found 2 swedish dissertations containing the words Michael Alvarsson.

  1. 1. Insulin-Degrading Enzyme : A link between insulin resistance and Alzheimer's disease

    Author : Helena Kullenberg; Marie Svedberg; Maria Kumlin; Thomas Nyström; Michael Alvarsson; Sophiahemmet Högskola; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Background: Prior research has demonstrated an elevated risk of Alzheimer's disease (AD) among individuals diagnosed with type 2 diabetes mellitus (T2DM). Insulin resistance is a potential common link between these conditions, and it is associated with AD due to the insulin-degrading enzyme (IDE), which also degrades amyloid-β (Aβ) in the brain. READ MORE

  2. 2. Metabolic and endocrine effects of SGLT2 inhibition

    Author : Per Lundkvist; Jan Eriksson; Lars Lind; Maria J Pereira; Michael Alvarsson; Uppsala universitet; []
    Keywords : SGLT2 inhibition; GLP-1 receptor agonism; DPP4 inhibition; NAFLD; prediabetes; type 2 diabetes; obesity; metabolic syndrome; glucagon.; Medicinsk vetenskap; Medical Science;

    Abstract : Obesity and type 2 diabetes (T2D) are two growing global health problems with similar comorbidity profiles. SGLT2 inhibitors (SGLT2i) improve blood glucose control and can relieve both T2D and obesity, as well as their associated health problems such as hypertension, kidney failure, and cardiovascular disease. READ MORE