Search for dissertations about: "Michael Höhle"

Found 3 swedish dissertations containing the words Michael Höhle.

  2. 1. Scan Statistics for Space-Time Cluster Detection

    Author : Benjamin Allévius; Martin Sköld; Michael Höhle; Paula Moraga-Serrano; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : Scan statistics are used by public health agencies to detect and localize disease outbreaks. This thesis provides an overview of scan statistics in the context of prospective disease surveillance and outbreak detection, presents a novel scan statistic to deal with the type of zero-abundant data that is often encountered in these settings, and—perhaps most importantly—implements this and other scan statistics in a freely available and open source R package. READ MORE

  4. 2. Dynamic Modelling of Communicable and Non-Communicable Diseases

    Author : Theresa Stocks; Michael Höhle; Tom Britton; Niel Hens; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : This thesis consists of two papers dealing with the stochastic dynamic modelling of one communicable and one non-communicable disease respectively. In the first paper we derive a patient- and organ-specific measure for the estimated negative side effects of radiotherapy using a stochastic logistic birth-death process. READ MORE

  5. 3. Stochastic dynamic modelling and statistical analysis of infectious disease spread and cancer treatment

    Author : Theresa Stocks; Tom Britton; Michael Höhle; Daniela De Angelis; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Mathematical modelling; infectious disease spread; cancer treatment; statistical inference; population dynamics; birth-death process; partially observed Markov process; Mathematical Statistics; matematisk statistik;

    Abstract : Mathematical models have proven valuable for public health decision makers as they can provide insights into the understanding, control and, ultimately, the prevention of diseases. This thesis contains four manuscripts dealing with stochastic dynamic modelling and statistical analysis of infectious disease spread and optimization of cancer treatment. READ MORE