Search for dissertations about: "Michele Solimena"
Found 2 swedish dissertations containing the words Michele Solimena.
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1. The Role of RNA Binding Proteins in Insulin Messenger Stability and Translation
Abstract : Although the reason for insufficient release of insulin in diabetes mellitus may vary depending on the type and stage of the disease, it is of vital importance that an amplified insulin biosynthesis can meet the increased need during periods of hyperglycemia. The insulin mRNA is highly abundant in beta cells and changes in insulin mRNA levels are, at least in part, controlled by altered rates of mRNA degradation. READ MORE
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2. Studies of the Pancreas: Implications for Type 1 Diabetes Aetiology
Abstract : Type 1 diabetes (T1D) is a disease of severe insulin deficiency through loss of β cells in the endocrine pancreas. The T1D dogma maintains that a precipitating event unleashes autoimmunity in at-risk individuals, often measured through autoantibodies against β cell antigens. READ MORE