Search for dissertations about: "Michele Vendruscolo"

Found 1 swedish dissertation containing the words Michele Vendruscolo.

2. 1. SOD1 Aggregation : Relevance of thermodynamic stability

   Author : Lisa Lang; Mikael Oliveberg; Michele Vendruscolo; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Aggregation; misfolding; Superoxide dismutase SOD1 ; Amyotrophic lateral sclerosis ALS ; unfolding; thermodynamic stability; Biochemistry; biokemi;

   Abstract : Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease affecting the upper and lower motor neurons causing muscle atrophy and paralysis followed by death. Aggregates containing superoxide dismutase (SOD1) are found as pathological hallmark in diseased ALS patients. READ MORE