Search for dissertations about: "Microangiopathy"
Showing result 1 - 5 of 21 swedish dissertations containing the word Microangiopathy.
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1. Microangiopathies of the human brain b immunohistochemical studies on extracellular matrix components in arterial vessels and endothelin
Abstract : Microangiopathies may cause ischemic brain lesions and are of fundamental importance in vascular dementia. Risk factors include high age, hypertension, diabetes and Alzheimer's disease. READ MORE
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2. Effects of PDGF-B gene inactivation in endothelial cell
Abstract : Platelet-derived growth factor-B (PDGF-B) is expressed by endothelial cells, neurons, macrophages and platelets. The relative importance of these cellular PDGF-B sources in vivo has been addressed by the creation of a conditional PDGF-B allele, which in the presence of a specific recombinase can be silenced in different tissues. READ MORE
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3. Diabetic skin microangiopathy : studies on pathogenesis and treatment
Abstract : Background: Most of late diabetic complications have their basis in a disturbed microcirculation, i.e. diabetic microangiopathy. READ MORE
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4. Microvesicles, skin microcirculation and clinical microangiopathy in type 1 diabetes
Abstract : Background: Type 1 diabetes is a proinflammatory and prothrombotic disease associated with a highly elevated risk of microvascular complications, including nephropathy, retinopathy, and neuropathy, as well as premature cardiovascular disease. Aim: this thesis sought to study plasma microvesicles (MVs) and skin microcirculation in relation to clinical microangiopathy in type 1 diabetes, to try to identify potential clinical biomarkers. READ MORE
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5. Studies of EHEC and the complement system in renal diseases
Abstract : This thesis addressed the diagnosis, pathogenesis and clinical course of specific renal diseases hemolytic uremic syndrome (HUS) and dense deposit disease (DDD). HUS may be associated with infection caused by Enterohemorrhagic Escherichia coli (EHEC) or with complement dysfunction due to complement mutations or auto-antibodies (atypical HUS, aHUS). READ MORE