Search for dissertations about: "Microglial activation"
Showing result 26 - 30 of 60 swedish dissertations containing the words Microglial activation.
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26. Microglia : health promoting pathways and therapeutic targets in ageing and neuroinflammation
Abstract : Microglia are the innate immune cells of the CNS with an embryonic origin and self-renew with a slow turnover throughout life. The health-promoting capacities of this cell are being acknowledged through updated and specific tools separating microglia from bone marrow-derived macrophages. READ MORE
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27. On cerebrospinal fluid markers of HIV-1 infection
Abstract : HIV-1 infects the central nervous system early in the course of infection and neurological complications are common in HIV-1-infected individuals. Approximately 20% of individuals with acquired immunodeficiency syndrome (AIDS) not treated with antiretroviral therapy develop a subcortical dementia, AIDS dementia complex (ADC). READ MORE
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28. Excitotoxic neurodegeneration in mouse brain : roles of immune cells and cytokines
Abstract : Excitotoxic neurodegeneration is a common feature in many neurological diseases. However, the roles of immune cells and cytokines in this process are unclear. To address this issue, we used knockout (KO) mice deficient in various immune cells or cytokines in our studies. READ MORE
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29. Neonatal hypoxic ischemic encephalopathy : inflammation and therapies
Abstract : Neonatal hypoxic ischemia (HI) is a severe condition characterized by a complex pathophysiology. The lack of oxygen (hypoxia) and blood flow (ischemia) leads to neuronal cell death via necrosis and apoptosis, and a consequent post-ischemic inflammation. HI brain injury may lead to seizures, cognitive and motor impairments, and death. READ MORE
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30. Host responses to human neural cell therapy in spinal cord injury
Abstract : Spinal cord injury (SCI) is a devastating condition without a cure. The SCI process comprises an initially mechanical trauma and a secondary cascade of events including a robust inflammatory and immune response. READ MORE