Search for dissertations about: "Microstructure drug release"

Showing result 1 - 5 of 10 swedish dissertations containing the words Microstructure drug release.

  2. 1. Microgels as drug delivery vehicles : loading and release of amphiphilic drugs

    Author : Yassir Al-Tikriti; Per Hansson; Magnus Bergström; Matthew Libera; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; microgel; amphiphilic drug; phase separation; micropipette; Raman microscopy; controlled release; drug delivery; SAXS; Pharmaceutical Physical Chemistry; Farmaceutisk fysikalisk kemi;

    Abstract : Polyelectrolyte microgels are used as delivery vehicles for amphiphilic drugs in, e.g., treatments of liver cancer by a method called trans-arterial chemoembolization. READ MORE

  4. 2. On Phase Behaviours in Lipid/Polymer/Solvent/Water Systems and their Application for Formation of Lipid/Polymer Composite Particles

    Author : Anna Imberg; Per Hansson; Krister Thuresson; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Physical chemistry; Biodegradable; CLSM; Composite Particles; Controlled Release; Cubic Phases; Drug Delivery; Flory-Huggins Theory; FT-PGSE-NMR; IPMS; Liquid Phase; Lipid Domains; Liquid Handler; Microspheres; Microstructure; Phase Behaviour; Phase Separation; Polymer Matrix; SAXS; Segregation; Sponge Phase; Swelling; Fysikalisk kemi; Physical chemistry; Fysikalisk kemi; fysikalisk och oorganisk farmaceutisk kemi; Physical and Inorganic Pharmaceutical Chemistry;

    Abstract : A new kind of lipid/polymer composite particle, consisting of a biodegradable polymer matrix with well-defined lipid domains, has been created. The lipid used is the water-swelling lipid monoolein (MO), which forms a reversed bicontinuous cubic diamond structure in aqueous solutions. READ MORE

  5. 3. Microstructure and liquid mass transport control in nanocomposite materials

    Author : Christoffer Abrahamsson; Chalmers tekniska högskola; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; magnetic alignment; permeability; colloidal gels; microgels; bond water; clay; flow; microstructure; nanocomposites; poly N-isopropylacrylamide ; porous materials; liquid mass transport; diffusion; diffusion NMR; particle aggregation; phase behavior; silica;

    Abstract : Some of the biggest problems currently facing the world are closely tied to unsolved technological challenges in the material sciences. Many materials have a porous microstructure that controls their overall properties. READ MORE

  6. 4. Diffusion Controlled Drug Release from Slurry Formed, Porous, Organic and Clay-derived Pellets

    Author : Erik Jämstorp Berg; Maria Strømme; Håkan Engqvist; Susanne Bredenberg; Pentti Tengvall; Nanoteknologi och funktionella material Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Diffusion; Drug delivery; Antithrombotic drugs; Highly potent opioids; Modeling; Clays; Polymers; Pellets; Beads; Materialvetenskap; Materials Science;

    Abstract : Coronary artery disease and chronic pain are serious health issues that cause severe discomfort and suffering in society today. Antithrombotic agents and highly potent analgesics play a critical role in improving the recovery process for patients being treated for these diseases. READ MORE

  7. 5. Identification and Variation of some Functionality Related Characteristics of Pharmaceutically Relevant Solid Materials and their Effect on Product Performance

    Author : Frauke Fichtner; Göran Alderborn; Åke Rasmuson; Peter Kleinebudde; Uppsala universitet; []
    Keywords : Pharmaceutics; Particle size distribution; Degree of agglomeration; Amorphous lactose; Matrix agglomerates; Drug release; Compactability; Tablet tensile strength; Particle fracture strength; Surfactant; Compression; Galenisk farmaci;

    Abstract : The aim of this thesis was to identify some functionality related characteristics of pharmaceutically relevant solid materials and to study the effect of their variation on processing behaviour and product performance. For this purpose, particles with different characteristics were prepared under a variety of conditions by crystal agglomeration, wet granulation and spray drying. READ MORE