Search for dissertations about: "Midgut carcinoid tumour"

Showing result 1 - 5 of 7 swedish dissertations containing the words Midgut carcinoid tumour.

2. 1. Midgut Carcinoid Tumours : New Diagnostic Procedures and Treatment

   Author : Staffan Welin; Eva T. Janson; Barbro Eriksson; Larry Kvols; Uppsala universitet; []
   Keywords : Medicine; Midgut carcinoid tumour; Chromogranin A; Carcinoid heart disease; Survival; Octreotide pamoate; Tyrosine kinase receptors; Platelet derived growth factor receptor; Epidermal growth factor receptor; Medicin;

   Abstract : Midgut carcinoid tumours are rare with an incidence of 0.5-2.1/100 000. The primary tumour is usually small and grows slowly but has almost always set metastases at diagnosis. READ MORE

4. 2. Tumour Biological Factors Characterizing Metastasizing Serotonin-producing Ileocaecal Carcinoids

   Author : Janet Lynn Cunningham; Eva Tiensuu Janson; Kjell Öberg; Irvin M. Modlin; Uppsala universitet; []
   Keywords : Internal medicine; endocrine tumour; midgut carcinoid; serotonin-producing neuroendocrine carcinoma; prognosis; morphology; tachykinin; connective tissue growth factor; islet autoantigen-2; morphology; carcinoid syndrome; Invärtesmedicin;

   Abstract : In this study, metastasizing serotonin-producing ileocaecal carcinoid tumours (MSPCs) were examined for biological characteristics that could be used to define clinically relevant subgroups within this patient population. Possible targets for new treatment options were also explored. READ MORE

5. 3. Midgut carcinoid tumours - biochemical and therapeutic aspects

   Author : Gunnel Westberg; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; carcinoid syndrome; valvular heart disease; 5-HT; chromogranins; octreotide; hepatic arterial embolization;

   Abstract : The biology of human midgut carcinoid tumour was studied experimentally in primary cell culture and clinically in patients with the midgut carcinoid syndrome. In cell cultures, tumour cells had a secretory pattern of 5-HTP, 5-HT and 5-HIAA specific for each tumour indicating individual regulation of synthesis/degradation. READ MORE

6. 4. Aspects on Diagnosis and Treatment of Gastrointestinal Neuroendocrine Tumours

   Author : Christina Swärd; Göteborgs universitet; []
   Keywords : Carcinoid; Endocrine pancreatic tumour; Neuroendocrine; Octreotide; Somatostatin receptor; Peptide receptor; Radionuclide therapy; Absorbed dose; Chromogranin A; Liver transplantation;

   Abstract : Aspects on Diagnosis and Treatment of Gastrointestinal Neuroendocrine Tumours Background. Gastroenteropancreatic neuroendocrine tumours (GEP-NETs) originate from endocrine cells of the intestinal mucosa and pancreas. READ MORE

7. 5. Endocrine tumour development : with special focus on chromosome arms 1p and 11q

   Author : Brita Nord; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Endocrine tumour; Follicular thyroid tumour; Malignant melanoma; Midgut carcinoid; Pheochromocytoma; Abdominal paraganglioma; Merkel cell carcinoma; MEN1; SDHD; RIZ;

   Abstract : The overall goal of this thesis has been to characterise the involvement of chromosome arms 1p and 11 q in the development of endocrine tumours. The MEN1 gene was analysed as a candidate tumour suppressor gene by screening for mutations in follicular thyroid tumours, malignant melanomas, pheochromocytomas, and abdominal paragangliomas. READ MORE