Search for dissertations about: "Migraine Disorders"

Showing result 6 - 10 of 10 swedish dissertations containing the words Migraine Disorders.

  2. 6. Physical comorbidity in twins with ASD or ADHD

    Author : Pei-Yin Pan; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Background: Individuals with autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD) have an increased risk for a range of physical disorders, which can complicate the clinical management, and increase impairment and experienced burden. The potential shared aetiological pathways underlying the association between ASD and ADHD behavioural phenotypes and physical disorders have received growing scientific interest. READ MORE

  4. 7. Genetic analysis and software development for studies on complex human traits

    Author : Lisette Graae; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Rapidly advancing genotyping and genome sequencing technologies have recently given us the opportunity to watch evolution at work. It turns out that the genome, like so many other workplaces, is rather messy. The sequences of no two humans are exactly alike, not even those of “identical” twins. READ MORE

  5. 8. Candidate genes and the dopamine system : possible implications in complex neurological and psychiatric disease

    Author : Silvia Buervenich; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Genetic; linkage; association; dopamine; Parkinsons disease; schizophrenia; bipolar disease; retinoid; aldehyde; toxicity.;

    Abstract : The mesencephalic dopamine (DA) system is strongly involved in the pathogenesis of Parkinsons disease (PD), where symptoms occur after the loss of the vast majority of DA neurons. An involvement of this system also in schizophrenia (SZ) and bipolar disease (BD) is suggested by the fact that DA receptor antagonists are among the most potent drugs in clinical use for the treatment of these conditions. READ MORE

  6. 9. Improved Techniques for High-Throughput Molecular Diagnostics

    Author : Mario Curcio; KTH; []
    Keywords : DNA; Molecular Diagnostics;

    Abstract : The amount of information derived from sequencing the humangenome is leading to an exponential increase in the rate atwhich genes and genetic disorders are mapped and characterized.As a consequence, the demand for genetic testing is alsodramatically increasing. READ MORE

  7. 10. Unraveling the role of NOTCH3 dysfunction in disease and for therapy development : a focus on CADASIL

    Author : Daniel V Oliveira; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The Notch signaling pathway, including the Notch3 receptor, is involved in many pivotal contexts of cell signaling and cell fate determination processes during development and in adulthood. Different mutations in the NOTCH3 receptor, which is highly expressed in vascular smooth muscle cells (VSMC), are associated with various diseases, including developmental disorders, several forms of cancer, and vascular dementia. READ MORE