Search for dissertations about: "Mikael Jonassohn"

Found 1 swedish dissertation containing the words Mikael Jonassohn.

  1. 1. Sesquiterpenoid unsaturated dialdehydes - Structural properties that affect reactivity and bioactivity

    University dissertation from Department of Organic Chemistry, Lund University

    Author : Mikael Jonassohn; [1996]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; mutagenic; autoxidation; dopamine D1 receptor; vanilloid receptor; structure-activity relationships; triacetic acid lactone; amino acids; reactivity; merulidial; warburganal; polygodial; Unsaturated dialdehydes; isovelleral; antimicrobial; cytotoxic; Polymer technology; biopolymers; Polymerteknik;

    Abstract : The natural unsaturated 1,4-dialdehydes warburganal (6), polygodial (14), isovelleral (55) and merulidial (56a) and their corresponding unconjugated aldehyde isomers (121), (15), (108) and (109a) were prepared, and their bioactivity and reactivity towards various nucleophiles were investigated. New synthetic routes to prepare (-)-6 and its isomer (+)-121 from (-)-14, and (+)-109a from (-)-56a, have been developed. READ MORE