Search for dissertations about: "Mikael Sigvardsson"

Showing result 6 - 8 of 8 swedish dissertations containing the words Mikael Sigvardsson.

  2. 6. Knock Knock Knock, Who is there? - Cell Crosstalk within the Bone Marrow

    Author : Jenny Stjernberg (Zetterblad); Mikael Sigvardsson; Jan-Ingvar Jönsson; Hanna Mikkola; Linköpings universitet; []
    Keywords : ;

    Abstract : This thesis is focused on the subject of cell-cell interaction. Our body is composed of cells, most of them are integrated in a network with other cells that together forms tissues and organs. Every cell type in these complex organs has its special task and location. READ MORE

  4. 7. What’s in a name? : Sub-fractionation of common lymphoid progenitors

    Author : Sasan Zandi; Mikael Sigvardsson; Avinash Bhandoola; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : The hematopoietic system is a highly dynamic organ developed in many multi-cellular organisms to provide oxygen, prevent bleeding and to protect against microorganisms. The blood consist of many different specialized cells that all derive from rare hematopoietic stem cells (HSCs) located in the bone marrow in mice and humans. READ MORE

  5. 8. Molecular mechanisms in lymphoid restriction : securing the B lineage fate

    Author : Josefine Åhsberg; Mikael Sigvardsson; Jan-Ingvar Jönsson; Charles G. Mullighan; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : With the work in this thesis I have aimed to deepen the understanding of the mechanisms behind the development of different blood cell lineages with a specific focus on B cell development.To understand the interplay between extracellular signaling and transcription factor networks in early lymphoid development we investigated the functional collaborations of FLT3 and IL7R. READ MORE