Search for dissertations about: "Minimal Residual Disease"
Showing result 16 - 20 of 38 swedish dissertations containing the words Minimal Residual Disease.
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16. Astatine-211 and Iodine Conjugates: Radiohalogenation and Preclinical Pharmacokinetics for Targeted and Pretargeted Radioimmunotherapy
Abstract : Endoradiotherapy using labelled tumour specific-monoclonal antibodies in the therapy of malignant disease is a therapeutic modality that is coming of age. While clearly defined tumours can be treated with surgery and/or chemotherapy, occult metastases requires adjuvant systemic treatment, e.g. READ MORE
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17. Prognostic factors, treatment and outcome in adult acute lymphoblastic leukemia : Population-based studies in Sweden
Abstract : Acute lymphoblastic leukemia (ALL) has poor prognosis in older/elderly adults and in high-risk/relapsed disease. Recommended treatment of ALL was evaluated (study I-IV). Data was obtained from the Swedish Acute Leukemia registries and from patient records.I. READ MORE
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18. Registry-Based Studies in Adult Acute Lymphoblastic Leukemia in Sweden : Survival and Quality of Life
Abstract : Acute lymphoblastic leukemia (ALL), a common child malignancy, also constitutes a minor fraction of adult cancer with approximately 50 new cases per year in Sweden. While the five-year overall survival (OS) in pediatric ALL is more than 90%, the prognosis in adults is dismal. READ MORE
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19. DNA methylation signatures in precursor lymphoid neoplasms : with focus on clinical implications & the biology behind
Abstract : Precursor lymphoid neoplasms, namely acute lymphoblastic leukemias (ALL) and lymphoblastic lymphomas (LBL), are characterized by an aggressive proliferation of malignant progenitor B- or T-cells. To improve risk classification at diagnosis, better prognostic and treatment stratifying biomarkers are needed. READ MORE
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20. Molecular monitoring of engraftment and leukemia relapse after allogeneic hematopoietic stem cell transplantation
Abstract : Relapse of the underlying disease, graft-versus-host disease (GVHD) and infections are the main complications after allogeneic hematopoietic stem cell transplantation (HSCT). A lower tumor burden increases the likelihood of cure after both chemotherapy and HSCT. READ MORE