Search for dissertations about: "Minimally invasive strategy"

Showing result 1 - 5 of 7 swedish dissertations containing the words Minimally invasive strategy.

  1. 1. Hyaluronan Derivatives and Injectable Gels for Tissue Engineering

    Author : Kristoffer Bergman; Tim Bowden; Jöns Hilborn; Jeffrey Hubbell; Uppsala universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Hyaluronan; Hydrogel; Tissue Engineering; Scaffold; Minimally invasive strategy; Bone morphogenetic protein; Hydroxyapatite; Bone; Cartilage; Tendon; Polymer chemistry; Polymerkemi;

    Abstract : The present work describes the preparation of hyaluronan derivatives and hydrogels with potential use in tissue engineering applications. A potentially injectable hydrogel consisting of hyaluronan and collagen was successfully used to grow neurons in vitro by encapsulation of neural stem and progenitor cells. READ MORE

  2. 2. Bone Enhancement with BMP-2 for Safe Clinical Translation

    Author : Marta Kisiel; Jöns Hilborn; Monica Wiig; Richard Oreffo; Uppsala universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICAL AND HEALTH SCIENCES; Bone repair; Bone healing; Bone morhogenetic protein-2; Osteogenesis; Extracelular matrix; Hyaluronan; Animal model; Orthopaedics; Ortopedi; Engineering Science with specialization in Materials Science; Teknisk fysik med inriktning mot materialvetenskap;

    Abstract : Bone morphogenetic protein-2 (BMP-2) is considered a promising adjuvant for the treatment of bone regeneration. However, BMP-2 delivery in a conventional collagen scaffold needs a high dose to achieve an effective outcome. Moreover, such dosage may lead to serious side effects. READ MORE

  3. 3. Ultrasensitive DNA sequencing using liquid biopsies enables precision medicine

    Author : Gustav Johansson; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Liquid biopsy; cell-free DNA; immune repertoire; next-generation sequencing; unique molecule identifier; GIST; γδ T cell;

    Abstract : Liquid biopsies are minimally invasive and allow repetitive sampling of body fluids. Analysis of cell-free tumor DNA in liquid biopsies can be used as a biomarker for cancer. However, in most clinically relevant liquid biopsies, cell-free DNA is present at low concentrations, contains minute tumor allele frequencies, and is highly fragmented. READ MORE

  4. 4. The application of microfluidic devices and multifunctional fibers in cancer diagnostics

    Author : Tharagan Kumar; Aman Russom; Fredrik Laurell; Gustaf Mårtensson; Johan Kreuger; KTH; []
    Keywords : Circulating tumor cells; microfluidics; point of care; inertial microfluidics; elasto inertial microfluidics; nano-cellulose; layer-by-layer; optical fiber; microflow cytometer.; Bioteknologi; Biotechnology;

    Abstract : Efficient separation and detection of rare cells in a mixed population is important in many biomedical applications. For instance, isolating and detecting circulating tumor cells (CTCs) from whole blood samples could allow for early cancer diagnosis and prognosis during treatment. READ MORE

  5. 5. Virtual Reality Simulations and Interventional Radiology

    Author : Berry Max; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : ;

    Abstract : INTRODUCTION: Use of virtual reality (VR) simulators in endovascular interventional education has become increasingly popular yet many questions surrounding this nascent technology remain unanswered. While progress has been made in other disciplines such as endoscopy and minimally invasive surgery, scientific evidence investigating endovascular simulations remains limited. READ MORE