Search for dissertations about: "Mitogen Activated Protein Kinases"

Showing result 16 - 20 of 47 swedish dissertations containing the words Mitogen Activated Protein Kinases.

  2. 16. Calcium calmodulin-dependent protein kinase signal transduction in cerebral arteries

    Author : Roya Waldsee; Lund Institutionen för kliniska vetenskaper; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CAMK; Ednothelin receptors; Calcium; gene regulation;

    Abstract : Cerebral arteries participate actively in the response that follows an episode of cerebral ischemia in man and rat. It has been shown that the vascular endothelin receptor expression is increased in stroke and organ culture. READ MORE

  4. 17. Interleukin-17 in non-allergic airway inflammation

    Author : Martti Laan; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; IL-17; airway inflammation; bronchial epithelial cells; neutrophils; T-lymphocytes; IL-8; IL-6; MAP kinases.;

    Abstract : Chronic bronchitis, chronic obstructive pulmonary disease (COPD), bronchial asthma and cystic fibrosis are common clinical disorders all characterized by airway neutrophilia. By releasing proteolytic enzymes and free oxygen radicals, neutrophils can contribute to the main features of these diseases such as airway obstruction, hypersecretion and remodelling. READ MORE

  5. 18. Role of MAP Kinases in the Life and Death of Beta-cells

    Author : Natalia Makeeva; Nils Welsh; Godfried Roomans; Thomas Mandrup-Poulsen; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell biology; diabetes; beta-cell; p38 MAPK; nitric oxide; apoptosis; Cellbiologi; Cell biology; Cellbiologi;

    Abstract : The development of diabetes mellitus depends on the balance between beta-cell proliferation and death. As mitogen-activated protein kinases (MAPK) may control this balance, the aim of this study was to investigate the events leading to MAPK activation in beta-cells and the consequences of these events. READ MORE

  6. 19. Signaling mechanisms underlying neural stem cell differentiation. Implications of BMPs, retinoids, and MAP kinases

    Author : Roland Faigle; Göteborgs universitet; []
    Keywords : neural stem cells; differentiation; BMP; ASK1; p38 MAP kinase; CNTF; retinoic acid;

    Abstract : Introduction: Neural stem cells are proliferating cells, derived from the nervous system with the ability to give rise to neurons, astrocytes, and oligodendrocytes. The molecular events and signaling pathways regulating neural stem cell differentiation are largely unknown. READ MORE

  7. 20. Regulation of signal transduction in the striatum by typical and atypical antipsychotic drugs

    Author : Kerstin Håkansson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Adenosine A2A receptor; basal ganglia; cAMP-dependent protein kinase; clozapine; DARPP-32; dopamine D 2 receptor; extracellular signal-regulated protein kinases 1 and 2; extrapyramidal side effects; glutamate AMPA receptor; haloperidol; knockout mouse; phosphorylation; schizophrenia; tyrosine hydroxylase.;

    Abstract : The only effective therapy for schizophrenia is based on the use of antipsychotic drugs. These substances act as dopamine D 2 receptor antagonists and can be classified as typical or atypical. Typical antipsychotics, e.g. READ MORE