Search for dissertations about: "Model Validation"

Showing result 1 - 5 of 693 swedish dissertations containing the words Model Validation.

  1. 1. Communication in the context of acute pain : Persuasion or validation?

    Author : Johan Carstens Söderstrand; Steven Linton; Katja Boersma; Tamar Pincus; Örebro universitet; []
    Keywords : SOCIAL SCIENCES; SAMHÄLLSVETENSKAP; SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Acute pain; communication; validation; reassurance; expectations for recovery; catastrophizing; recall; misdirected problem solving; psycho-logical flexibility;

    Abstract : Historically, the dominating theoretical framework for communication in the context of acute pain is reassurance. An inherent assumption of this framework is that the person in pain needs to have their fears and doubts removed and be educated, or persuaded, that the pain problem is not dan-gerous. READ MORE

  2. 2. Covariate Model Building in Nonlinear Mixed Effects Models

    Author : Jakob Ribbing; E. Niclas Johnsson; Mats O. Karlsson; Janet Wade; Uppsala universitet; []
    Keywords : Pharmacokinetics Pharmacotherapy; Pharmacokinetics; Pharmacodynamics; Modeling; Covariate selection; Stepwise selection; Covariate analysis; Methodology; Model validation; Model evaluation; Type-2 diabetes; Beta-cell function; Meta analysis; Cross-validation; Least absolute shrinkage and selection operator; Pharmacometrics; ED optimization; Farmakokinetik Farmakoterapi;

    Abstract : Population pharmacokinetic-pharmacodynamic (PK-PD) models can be fitted using nonlinear mixed effects modelling (NONMEM). This is an efficient way of learning about drugs and diseases from data collected in clinical trials. READ MORE

  3. 3. Drug Analysis : Bioanalytical Method Development and Validation

    Author : Mikaela Malm; Yngve Bergqvist; Anders Colmsjö; Uppsala universitet; []
    Keywords : Analytical chemistry; African trypanosomiasis; calibration model; chiral chromatography; dried blood spots; eflornithine; evaporative light-scattering detection; HIV AIDS; lamivudine; liquid chromatography; malaria; nevirapine; piperaquine; pneumonia; solid-phase extraction; sulfadoxine; sulfamethoxazole; validation; zidovudine; Analytisk kemi;

    Abstract : This thesis describes bioanalytical methods for drug determination in biological matrixes, with drugs in focus used against diseases largely affecting low-income countries. Solid-phase extraction is used for sample cleanup, and processed samples are analyzed by liquid chromatography. READ MORE

  4. 4. Definition and validation of requirements management measures

    Author : Annabella Loconsole; Jürgen Börstler; Björn Regnell; Umeå universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Requirement; Measures; Volatility; Theoretical Validation; Empirical Validation; Prediction Model; Correlational Study; Subjective Estimation.; Software engineering; Programvaruteknik;

    Abstract : The quality of software systems depends on early activities in the software development process, of which the management of requirements is one. When requirements are not managed well, a project can fail or become more costly than intended, and the quality of the software developed can decrease. READ MORE

  5. 5. On Standardized Model Integration : Automated Validation in Aircraft System Simulation

    Author : Robert Hällqvist; Petter Krus; Magnus Eek; Robert Braun; Henrik Tidefelt; Linköpings universitet; []
    Keywords : ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY;

    Abstract : Designing modern aircraft is not an easy task. Today, it is not enough to optimize aircraft sub-systems at a sub-system level. Instead, a holistic approach is taken whereby the constituent sub-systems need to be designed for the best joint performance. READ MORE