Search for dissertations about: "Mohamed Sagar"

Found 1 swedish dissertation containing the words Mohamed Sagar.

  1. 1. The importance of the CYP2C19 polymorphism for disposition and effects of omeprazole treatment

    University dissertation from Stockholm : Karolinska Institutet, -

    Author : Mohamed Sagar; Karolinska Institutet.; Karolinska Institutet.; [1999]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Omeprazole; CYP2C19; H. pylori; gastrin; intragastric pH; vitamin B12;

    Abstract : CYP2C19, catalyzes the metabolism of omeprazole and several other drugs. About 3% of Caucasians are poor metabolizers (PM) of these drugs. The goal of this thesis was to evaluate the importance of CYP2C19 polymorphism for disposition and clinical effects of omeprazole treatment in healthy subjects and in patients with acid related disorders. READ MORE